I-Timolol iyilungiso le- antiglaucoma ye-ophthalmologic, eluhlu lwamachiza abalulekileyo kunye abalulekileyo. Cinga ulwazi olusisiseko kumathambeka kwamehlo eTimolol, apho isiguli sifuna xa usebenzisa le mayeza.
Ukubunjwa kunye nefom yeTimolol yokulungiselela
Njengomthetho, amaconsi esiso seTimolo ayatholakala kwiibhotile ze-plastic-droppers. Icandelo elisebenzayo leziyobisi i-timolol ngesimo se-maleate (i-maleic acid isile). Inomxholo osebenzayo kula manzi angama-0.5% (5 mg timolol kwisisombululo se-1 ml) okanye i-0.25% (2.5 mg i-timolol kwisisombululo se-1 ml).
IziHlomelo zamehlo amaconsi e-timolol:
- i-chloride ye-sodium;
- benzalkonium chloride;
- i-sodium dihydrogen phosphate dihydrate;
- i-disodium phosphate dodecahydrat;
- idideyiti edetate;
- amanzi adibeneyo.
Izibonakaliso zokusetyenziswa kwamathambo aseTimolol:
- ocetytension (ukwanda kwe-intraocular pressure);
- glaucoma evulekile engapheliyo;
- I-glaucoma yokuvala (kunye ne-miotics);
- i-glaucoma yesibili (i-uveal, posttraumatic, aphakic);
- I-glaucoma yama-Congenital (ngokungaphumeleli kwamanye amanyathelo okwelapha).
I-Pharmacological action yamehlo ahlahlayo eTimolol
Into ephezulu yeziyobisi i-blocker ye-beta-adrenergic receptor blocker ekhethileyo, engekho-ye-betrenoric receptor blocker (ithuluzi elinciphisa ukubamba kwemizwa yesibindi).
Umphumo weziyobisi kubangelwa ukuhla kwe-secretion ye-intraocular fluid, kodwa ukunyuka kwe-outflow ayikhutshwe. Amaconsi e-timolol awachaphazeli ubukhulu bomfundi, indawo yokuhlala kunye nokukhawulwa, kunye nokuvumela ukubekwa kweliso lwe-intraocular (ophthalmotonus) ngexesha lokulala.
Ukunciphisa i-ophthalmotonus kufezekiswe kokubili kunye nokuqala kwengcinezelo ye-intraocular. Umphumo ubonwa, njengommiselo, imizuzu engama-20 emva kokusetyenziswa kwesilwanyana, kufinyelela kwisithuba esiphezulu emva kweeyure eziyi-1 ukuya kwezi-2. Ubungakanani bezenzo zamathambo we-timolol malunga neeyure ezingama-24.
I-Timolol i-maleate ixhaswa ngokukhawuleza nge-cornea. Kwisixa esincinci, isilwanyana singena kwi-systemic circulation nge-absorption ngokusebenzisa iinqanawa ze-conjunctiva kunye ne-tear trap.
Indlela yolawulo kunye nemodi ye-dosing timolol
Ngokwemiyalelo yokusebenzisa isohlwayo kwamehlo eTimolol, isilwanyana siphethwe enye ye-1-2 rhoqo ngamaxesha kwisigxobo esincinci se-eye ethintekileyo. Ukuxinwa kwesisombululo kucetyiswa ngugqirha ngabanye. Ukuba kukho ukungasebenzi okwaneleyo, kufuneka uqhubeke usebenzisa isisombululo esiphezulu. Emva kokuzinzisa ukunyanzeliswa kwe-intraocular, umthamo weziyobisi wehla ukuya ku-1 ukuhla kanye ngosuku.
Isilwayo senzelwe ukusetyenziswa kwexesha elide (ngokuqhelekileyo, ukuya kwiiveki ezi-6). Ubungakanani bekhosi yonyango kuxhomekeke kwisikolo sesifo. Ikhefu ekusebenziseni amaconsi e-timolol okanye utshintsho kwi doseki lwenziwa kuphela kwisinconywa soogqirha.
Imiphumo emibi ye-Timolol Drops:
- ukunciphisa ukubetha;
- i-anesthesia;
- indawo yokwakheka komzimba;
- iimpawu zokucaphukisa.
Kwezinye izigulane ezinokusetyenziswa ixesha elide kweziyobisi, iziphumo zenkqubo ziyakwenzeka:
- i-arrhythmia;
- bradycardia;
- hypotension;
- ukuphefumula okufutshane ;
- bronchospasm;
- ukungcola.
Ukungqinelana nokusetyenziswa kwamaconsi eTimolol:
- i-asthma ye-bronchial;
- isifo esingenasifo sokuphefumula;
- sinus bradycardia;
- i-atrioventricular blockkade ye-II ne-III degree;
- isifo sikashukela;
- ukuhluleka kwentliziyo;
- ukukhulelwa kunye nokuhlaselwa;
- i-hypersensitive to the components of the drug.
Timolol - ezifanayo
I-Timolol ngokubonisana nodokotela ingathatyathwa ngamachiza anefuthe elifanayo lemveliso. Ezi ziquka:
- I-Asopt;
- Fotil;
- Okumed;
- Xalatan;
- Pilocarpine;
- Betoptik.