Ngaphambili , isilonda esiswini sasinxulumene kuphela nokuphazamiseka kokutya kunye nokusetyenziswa kakubi kotywala, ngelixa iyona nto ibangela isifo yi-Helicobacter pylori bactorium. Ukuxothwa kwonyango ngumgangatho osemgangathweni wobugcisa obenzelwe ukutshabalalisa le microorganism nokuqinisekisa ukusebenza ngokuqhelekileyo kwenkqubo yokutya.
Isicwangciso sokuphulukisa unyango lweMaastricht
Inani leemfuno zinikezelwa kwiinkqubo zonyango:
- qoqosho;
- ukugcinwa kokupheliswa kwinqanaba eliphezulu;
- lula kwaye kulula;
- ukungabikho kwempembelelo yemimandla engamelana neebhaktheriya kwixesha lezonyango;
- Inani eliphantsi leempembelelo;
- ubukho befuthe kwinkqubo yesilonda.
Ukufezekisa ezi njongo, izicwangciso zihlala ziphuculiswa kwaye zihlengahlengiswa ngokuhambelana nezigqibo ezithathwe kwiiNgqungquthela zezoNyango zezeMpilo zaseMaastricht.
Kuza kubekho, kukho ubuchule obunamacandelo amathathu kunye ne-quadrotherapy, siza kubaqwalasela ngokubanzi iinkcukacha.
Ulwaphulo oluthathu lwequmrhu likaHelikobakter Pilori
Inkqubo ephindwe kabini yintlobo ezimbini: ngokusekelwe kwilungiselelo le-bismuth kunye nesiseko se-inhibitors yepompo ye-proton yamaseli e-parietal.
Kwimeko yokuqala, unyango lokupheliswa kwezilonda zesilonda luquka:
- I-Bismuth (120 mg) njenge-colloidal subcitrate okanye i-gallate okanye i-subalicylate.
- Tinidazole okanye iMetronidazole. Ngamanye ama-250 mg.
- ITetracycline i-0.5 g.
Zonke iyeza kufuneka zithathwe amaxesha amane ngosuku ngemilinganiselo ebonisiweyo. Inkqubo yokonyango i-1 iveki.
Kwimeko yesibini, icebo libukeka kanje:
- I-Omeprazole (20 mg) kunye ne-Metronidazole (0.4 g amaxesha amathathu ngosuku) kunye nezinye i-antibiotics - i-Clarithromycin (250 mg kabini kwiiyure ezingama-24).
- I-pantoprazole 0.04 g (40 mg) kunye ne-Amoxicillin 1 g (1000 mg) amaxesha amabini ngosuku, kunye neClaithithromycin 0.5 g kunye namaxesha ama-2 ngosuku.
Iproton pump inhibitors kufuneka ithathwe ngamaxesha ama-2 nganye iiyure ezingama-24.
Kwimeko yokugqibela, i-Pantoprazole ingathatyathwa yi-Lanoprazole kwisilinganiso se-30 mg kabini ngosuku.
Ubungakanani bonyango oluchaziweyo lunentsuku ezi-7.
Kubalulekile ukuba uqaphele ukuba ukupheliswa kwe-80% kuthathwa njengempumelelo, nangona oku akuthethi ukuba ibhaktiriya yachithwa ngokupheleleyo. Ngenxa yokusetyenziswa kweziyobisi ezichasene ne-antibacterial, inani le-microorganisms likhawuleza kwaye liyancitshiswa kakhulu kwaye ngexesha lokuhlalutya abangabonakali. Ekupheleni kwekhosi i-colony iya kubuyiselwa kwaye umqolo wonyango olandelayo uya kufuneka.
Ulwaphulo olunezinyathelo ezine zokupheliswa kwe-Helicobacter pylori
Iskimu esibhekiselweyo siyabelwa xa kwenzeka iziphumo ezingaphumelelanga emva kokunyangwa kwamacandelo amathathu eentlobo ezikhankanywe ngasentla. Iquka loo mayeza:
- Ukulungiswa kwe-bismuth yi 120 mg amaxesha amane ngosuku.
- Umxube we-antibiotics - iTetracycline (amaxesha amane ngosuku nge-500 mg) nge-Metronidazole (250 mg amaxesha amane kwiiyure ezingama-24) okanye i-Tinidazole (amaxesha amane ngosuku nge 250 mg).
- Iproton pump inhibitor iziyobisi (enye yeyesithathu) yi-Omeprazole (0.02 amagremu) okanye iLansoprazole (0.03 amagremu) okanye i-Pantoprazole (0.04 grams) kabini imihla ngemihla.
Ubungakanani bexesha lonyango aludluli kwiveki enye.
Xa ukhetha amachiza e-antibacterial, kubalulekile ukuqwalasela ukuchasana kwe-helicobacter pylori kwiibhente ezinjalo. Kuyaziwa ukuba ii-microorganisms zincinci kwi-Amocycillin naseTetracycline. Kukho amaxesha okuphuhliswa okungaqhelekanga kuClaithithromycin (malunga ne-14%). I-immununity ephezulu ijongwa kuMetronidazole (malunga nama-55%).
Uphando olutsha lwezonyango luye lwabonisa ukuba ukuphulukana ngokuphumelelayo kuyacetyiswa ukuba kusetyenziswe iziyobisi ezitsha zamachiza, umzekelo, uRifabutin kunye neLevofloxacin. Ukukhawuleza ukuphilisa izilonda kwiindawo ezinamaqabunga esiswini, kuyacetyiswa ukuba ukongeze ukongeza iSophalcon kunye ne-Cetraxate.