Sjogren's Syndrome - zonke iimpawu zonyango oluphumelelayo

I-Sjogren's syndrome yisifo esizimele esingabonakaliyo esibangela umonakalo owenziwe kumathambo. Ukususela kwinkqubo ye-pathological, i-ecocrine-glands - i-stlands kunye neentlanzi zentlungu-zihlupheke kakhulu. Kwiimeko ezininzi, lesi sifo sinehambo engapheliyo.

I-Sjogren's Syndrome - yintoni esi sifo?

Kwiinkimbinkimbi zeempawu zesifo esomileyo okokuqala ngqalelo ihlawulwe nguSweden ophthalmologist uShegren engaphantsi kweminyaka eyikhulu edlulileyo. Wafumana inani elikhulu lezigulane zakhe ezaziza kuye izikhalazo zomelele emehlweni, ezinye iimbonakalo ezifanayo: ukuvuvukala okungapheliyo kwamalungu kunye ne-xerostomia - owomile we-mucosa yomlomo. Ukuqwalasela umdla abanye oogqirha kunye nososayensi. Kwavela ukuba le ntsholongwane iyinto eqhelekileyo kwaye ukulwa nayo idinga unyango oluthile.

Sjogren's syndrome - yintoni na? Esi sifo esingapheliyo sisebenza ngokubhekiselele kwimvelaphi yokungaphumeleli kwisistim somzimba. Umzimba uthatha iiseli zaso kwiiseli zangaphandle kwaye uqala ukuhlakulela ngokutsha izikhuhlane. Ngokuchasene nale mvelaphi, inkqubo yokuvuvukala ikhula, ekhokelela ekunciphiseni kwimisebenzi yeengqungquthela zecandelo lokungcebeleka kwangaphandle - ngokuqhelekileyo i-saliary and lamal.

I-Sjogren's Syndrome - Izizathu

Ukutsho ngokungagqibekanga ukuba kutheni izifo ezizimele zihlakulele, iyeza lisekho. Ngoko ke, apho i-syndrome eyomileyo ye-Sjogren ivela kuyo imfihlelo. Kuyaziwa ukuba i-genetic, immunological, hormonal kunye nezinye izinto zangaphandle zithatha inxaxheba ekuphuhlisweni kwesi sifo. Kwiimeko ezininzi, ii-virus ezifana ne-cytomegalovirus, i-Epstein-Barr, i-herpes, okanye izifo ezifana ne-polymyositis, i-systemic scleroderma, i-lupus erythematosus, i-rheumatoid arthritis ibangela ukuphuhliswa kwesifo.

Sjogren's Syndrome

Kukho iintlobo ezimbini ezibalulekileyo zokugula. Kodwa bafana okufanayo. Ukucwina kweembrane ezinamaqabunga kumabini omabili kuvela ngenxa yokungena kwe-lymphocytic yeengqungquthela ze-exocrine kunye nomzila wesisu kunye nesiphene sokuphefumula. Ukuba eso sifo siphula njengesifo esizimeleyo kwaye akukho nto iqala ukubonakala kwayo, ke le yintloko yesifo seSjogren.

Sjogren's Syndrome

Njengoko uqeqesho lubonisa, kwezinye iimeko, lesi sifo senziwa ngokumalunga nemvelaphi yezinye izifo. Ngokwezibalo, i-syndrome yesibini eyomileyo ifumaneka kwi-20 - 25% yezigulane. Kufakwa xa isifo sifana neenkalo zeengxaki ezifana ne-rheumatoid arthritis, i-dermatomyositis, i-scleroderma kunye nezinye ezinxulumene nezilonda zamathambo axhumeneyo.

I-Sjogren's syndrome - iimpawu

Zonke izibonakaliso zesifo zihlulwe zibe zi-glandular kunye neyesinyithi. Inyaniso yokuba i-Sjogren's syndrome isasazeke kwiingqungquthela ezilahlayo ziyakwazi ukuqonda ngokutshisa, "isanti" emehlweni. Uninzi umkhalazo wesikhumba seqhenqa esinzima. Ngokuqhelekileyo amehlo agubha obomvu, kwaye emacaleni abo aqokelela imveliso ebomvu. Njengoko eso sifo siyaqhubeka, i-photophobia ikhula, iliso lilahla libonakala lincinci, ubuqhetseba obubonakalayo bubonakala. Ukwanda kweengqungquthela ezilahlayo kuyinto engavamile.

Impawu zobunjwa be-Sjogren, ezithintela iingqungquthela zomsindo: umlomo oomileyo emlonyeni, umda obomvu, umlomo. Ngokuqhelekileyo, izigulane zihlaselwa , kwaye, ngaphezu kweengqungquthela zesigxina, ezinye zeengqungquthela ezisondeleyo zanda. Ekuqaleni, eso sifo sibonakalisa kuphela ngokuzikhandla ngokomzimba okanye uxinzelelo lwengqondo. Kodwa kamva ubomileyo buba yinto engapheliyo, imilomo igubungelwe ngamagqabha aqhuba, okwandisa umngcipheko wokujoyina isifo sofayo.

Ngamanye amaxesha, ngenxa yokomisa kwi-nasopharynx, ii-crusts ziqala ukwenza kwiipumphu kunye neengcambu zophicotho, ezingakhokelela kwi-otitis kunye nokulahlekelwa kwindlebe yesikhashana. Xa i-pharynx kunye neentambo zezwi zixakeke kakhulu, kukho ukuphazamiseka nokugqithisa. Kwakhona kwenzeka ukuba ukuphulwa kokugwinya kuholele kwi-atrophic gastritis. Ukuxilongwa kubonakaliswe yisicongconi, ukunyuka kwesondlo, isisindo kwisigodi se-epigastric emva kokutya.

Ubonakaliso obungaphezulu kweempawu zesifo esiyinkimbinkimbi ye-Sjogren's syndrome bukeka ngathi:

• intlungu;
• ubunzima beentlungu kunye namajoyina ekuseni;
• buthathaka;
• ukugqithisa okuncinci kwegazi okuqhubekayo malunga nemvelaphi yezilonda zesisulu;
• i-neuritis ye- facial or trigeminal nerons;
• ukugqithisa okukhulu kwi-trunk kunye nemida;
• owomileyo wesini.

I-Sjogren's syndrome - ukuxilongwa ngokungafani

Ingcaciso yesifo isekelwe ngokubhekisele kwi-xerophthalmia okanye i-xerostomia. Olu hlobo lokugqibela lufunyaniswa ngolu hlobo lwe-sialography, ukukhawulwa kwe-parotid kunye ne-salivary gland biopsy. Ukuxilongwa kwe-xerophthalmia, uvavanyo lweSchirmer lwenziwe. Omnye umgca womgca wephepha ococekileyo ubeka phantsi kwekhosidi ephantsi kwaye ushiye ixesha elithile. Abantu abaphilileyo, emva kwemizuzu engama-5, malunga ne-15 mm yomgca uya kuba yimanzi. Ukuba i-Sjogren's syndrome iyaqinisekiswa, ukuxilongwa kubonisa ukuba ayikho ngaphezu kwe-5 mm emanzi.

Ukuxilongwa ngokwahlukileyo kubalulekile ukuba ukhumbule ukuba i-NLS ingahlakulela ngokufana nokuxilongwa kwe-thyroiditis, i-percinosis anemia, isifo seziyobisi. Inkcazo ye-primary syndrome eyomileyo iququzelelwe kakhulu ngokufumanisa izifo ezikhuselekileyo ze-SS-B. Kunzima kakhulu ukufumanisa isifo se-Sjogren ngesifo se-rheumatoid arthritis, kuba umonakalo odibeneyo uqala ixesha elide ngaphambi kokubonakala kwempawu zobomileyo.

I-Sjogren's syndrome - iimvavanyo

Ukuxilongwa kwesi sifo kubandakanya ukuqhuba iimvavanyo zelabhoratri. Xa ufumene isifo sesifo sikaSjogren, ukuhlalutya kubonisa malunga nezi zilandelayo ziphumo:

1. Kuvavanyo jikelele lwegazi, i-ESR ekhawulezileyo, i-anemia kunye ne-low white cell count count are determined.
2. I-OAM ibonakaliswe ubukho beeprotheni.
3. Iprotheni iphinda iphakanyiswe kuhlalutyo lwegazi. Ukongezelela, uvavanyo lubonisa iindawo eziphezulu ze-rheumatoid factor.
4. Uvavanyo olulodwa lwegazi ngenxa yobukho be-antibodies kwi-thyroglobulin kwi-35% ibonisa ukwanda kwenkxalabo yabo.
5. Iziphumo ze-salivary gland biopsies ziqinisekisa iimpawu ze-Sjogren's syndrome.

Sjögren's Syndrome - unyango

Le ngxaki enkulu, kodwa ayiyikubulala. Ukuba ubeka ingqalelo kwiimpawu zayo ngexesha kwaye xa ufumanisa unyango lweSjogren isifo, ungahlala nayo, uzive ukhululekile nalo. Into ephambili kwizigulane akunakulibala ngokubaluleka kwendlela yokuphila enempilo. Oku kuya kunceda ukuqinisa imo-mpilo, ayiyi kuvumela inkqubo ye-pathological ukuba iphuhlise ngokukhawuleza kwaye iyanciphisa kakhulu umngcipheko weengxaki.

Ngaba kunokwenzeka ukuphilisa i-Sjogren's syndrome?

Xa ukuxilongwa kuqinisekiswa, isigulane sithola iingcebiso zonyango. I-Sjogren's syndrome iyaphathwa ngempumelelo namhlanje, kodwa ayinakwenzeka ukuba isuswe ngokupheleleyo eso sifo. Ngenxa yeso sizathu, kwenziwa kuphela unyango lwezonyango. Iziphumo zokuvavanya umgangatho wonyango luqhelekileyo ukubonakaliswa kwezonyango zesifo. Ukuba zonke iinjongo zonyango zinceda, izibonakaliso zelabhoratri kunye nomfanekiso wakhe wezobugcisa ziphucula.

I-Sjögren's Syndrome - Iingcebiso zeCliniki

Ulwaphulo lwe-syndrome elomileyo lubandakanya ukunciphisa impawu kwaye, ukuba kuyimfuneko, ukulwa nesifo esisemgangathweni. Ngaphambi kokonyangwa kwe-Sjogren's syndrome, ukuxilongwa kukwenziwe. Emva koko, njengommiselo, ezo ndlela zisetyenziswa:

• i-glucocorticoid i- Prednisolone (iskimu kunye nesilinganiselo sinqunywe ngokwemiqathango kuxhomekeke kubukhulu be-syndrome kunye nobukhulu beempawu zayo);
• ii-angioprotectors - i-Parmidin, i-Solcoseryl;
• i-immunomodulator Splenin;
• Heparin ye-anticoagulant;
• I-Contrikal okanye iTrasilol - iziyobisi eziyeka ukuveliswa kwee-enzyme ze-proteolytic;
• Zioostatics - I-Chlorbutin, i-Azathioprin, i-Cyclophosphamide (isincoma ukuba ithathe i-glucocorticoids).

Ukulahla umlomo owomileyo, susela. I-eye syndrome yamehlo iphathwa nge-instillation ye-saline, i-Hemodesis. Iibhubhu ezinomileyo kunye ne-trachea zingaphathwa ngeBromhexine . Ngokuvuvukala kweengqungquthela ze-Dimexide, i-Hydrocortisone okanye i-Heparin ziyanzima. Ngamanye amaxesha umlomo owomileyo ukuxilongwa kwe-Sjogren's syndrome kukhokelela ekuphuhlisweni kwezifo zamazinyo. Ukuzikhusela, kufuneka uzinakekele ukuhlambulula umlomo.

Isifo sikaSjogren - unyango kunye nezilwanyana zomntu

I-syry syry is complex of signs and signs. Ngabo bonke kungcono ukulwa ngokuqhelekileyo. Kodwa ngamanye amaxesha ngeSjogren's syndrome, iindlela eziqhelekileyo zisetyenziselwa ukuncedisa imeko yesigulane. Ezinye izigulane, umzekelo, phawula ukuba i-drops yeehlo ezenziwe kwi-dill kunye nejusi yezambane zisebenza ngokugqithiseleyo kunokuba utywala otywala imithi.

Ukunquma kwemifuno yokuhlanza

Izithako:

• i-chamomile izimbali - 1 isipuni;
• Amagqabantshintshi - 1 tbsp. l.;
• amanzi - 1 iglasi.

Ukulungiselela nokusetyenziswa:

1. Ukuxuba i-Grasses kunye nokusika.
2. Amanzi abilayo kwaye uthele emxube owomileyo.
3. Iyeza kufuneka liphule imizuzu engama-40.
4. Emva kokuhlunga kulungele ukusetshenziswa.

I-Sjogren's syndrome - isalathisi

Esi sifo siqhubeka ngaphandle kokusongela ubomi. Kodwa ngenxa yakhe, umgangatho wobomi bezigulane uhlahloka ngokuphawulekayo. Unyango lunceda ukukhusela iingxaki kwaye kugcina amandla abasebenzi abasebenza ngabantu abadala - Isifo sikaSjogren kubantwana siqabile kakhulu. Ukuba unyango aluqalanga, lesi sifo singakhula sibe yindlela ephosakeleyo, leyo, xa ukusuleleka kwesibini, njenge- bronchopneumonia , sinusitis okanye i-tracheitis ephindaphindiweyo, ngamanye amaxesha kuqhuba ukukhubazeka.