Yinjani le nkqubo?
Ukulima ukukhula kwexesha elide kuyinto ehambelana nenkqubo ephezulu kunye nenkqubo eyinkimbinkimbi efuna i-laboratory ekhethekileyo, enezixhobo ezixabisekileyo. Kungenxa yale nxalenye engekho onke amaziko achaphazelekayo kwi-IVF kunye nokucwangciswa kokukhulelwa kunika inkqubo enjalo.
Le ndlela ibandakanya ukuhlalwa kwemibusi ngaphambi kwesigaba se-blastocyst. Amacandelo asetyenzisiweyo ngaphambili aphakanyiswa ukufakelwa kwembungu emzimbeni wesifazane kwinqanaba lokuqhekeka kwalo, okokuthi. kwiintsuku ezingama-2-3. Le nyaniso yanciphise impumelelo ye- IVF kwaye inkqubo yokudluliselwa kombindi kwakufuneka iphindwe kaninzi.
Ukutshintshwa kwendawo yokulima embryo in vitro kuye kwenza ukuba kubekho uphuhliso lwezobuchwepheshe kwintsimi ye-embryology, ngenxa yentuthuko ekhethekileyo kwintsimi yonyango lokuzala. Le ndlela, esetyenziselwa ukukhokela iiklinikhi zokuzala emhlabeni, iquka ukudibanisa ixesha elide kunye nombindi weendawo ezizodwa (SICM / SIBM kunye ne-Assistative Embryo / iBlast Assist).
Kuyafaneleka ukuba uqaphele ukuba le nqubo ayinakukwazi ukukho ngaphandle kokusetyenziswa kwesicatshulwa esikhethekileyo-incubator ye-gas. Kukukho ukuba ezinye iigygotes zifakwe kunye nomgangatho wesondlo. Emva kweentsuku ezingama-4-6, iingcali zithatha i-blastocyst kule fowuni kwaye ihlole ukusebenza kwayo. Ngokwezibalo zedatha, malunga nama-60-70% amaqanda azaliswe ngexesha le-IVF, kunokwenzeka ukuba ufumane ii-embrosi eziqhelekileyo.
Ziziphi iingenelo zokulima ixesha elide leembrusi?
Le ndlela ye-IVF ivumela, okokuqala, ukuphucula umgangatho wokukhethwa (ukukhethwa) kwaye usebenzise ama-embryythi kuphela anokwaneleyo okubizwa ngokuba yi-plant implantation. Ngamazwi alula, ukusebenzisa le ndlela kwandisa kakhulu amathuba okukhulelwa emva kwe-IVF.
Ukongezelela, phakathi kwezinye izinto ezinokubaluleka kwexesha elide lokulima ukubizwa ngokuthi:
- kuncipha kwinani le-chromosomal engafanelekanga kwimibyusi ethathelwa kwisigaba se-blastocyst;
- le ndlela yindlela yokuphila ngokuthelekisana ne-embryo ukudlulisela kwiintsuku ezi-3;
- ukulima okude kwanele ukubeka imibungu engama-1-2 kwisibilini sesisu, i-tk. ubuchule bokuhlanganiswa nokuphuhliswa kakhulu;
- umngcipheko wokwenza loo nkathazo njengoko ukukhulelwa kwe-ectopic kuncitshiswa kakhulu.
Ziziphi iingxaki ezi ndlela?
Emva kokuqonda ukuba oku kukhula kwexesha elide le gametes kunye nama-embrosi, ekuxelele malunga neenzuzo zale ndlela ye-IVF, kuyimfuneko ukuba ungayikhohlwa malunga nokungaphumeleli kwindlela.
Iyokuqala kwezi zinto kukuba zonke iibrashi ezilinywayo zikhula zibe yi-blastocyst, kwiimeko ezininzi kuphela ezingama-50% zazo zifikelela kweli nqanaba lophuhliso. Ukunikezelwa kwesi sici, le ndlela inokwenzeka kuphela ukuba ngomhla wesithathu wokulima, kubakho ubuncinci 4. Kwinqanaba eliphantsi, amathuba okufumana ubuncinane bodwa, afinyelele kwisigaba se-blastocyst, iphantsi kakhulu.
Okwesibini ukungahleleki kunokuthiwa ngumzuzu ukuba nangona i-embryu ifinyelela kwisigaba sokuphuhliswa kuyimfuneko yokutshintshwa, le nto ayiniki isiqinisekiso sokuthi ukufakelwa kuyo kuya kuphumelela kwaye ukukhulelwa kuza kuza.