Kuyaziwa ukuba abantu abanexinzelelo lwengcinezelo ixesha elide basengozini enkulu yokungenwa kwe-myocardial, ukuphazamiseka, ukutshintsha kwiinqanawa ze-fundus kunye nokungaphumeleli kwe-renal. Ngoko ke, izigulane ezinokunyuka okuqhubekayo kwingcinezelo yegazi, zibonisa ukusetyenziswa kwezidakamizwa ezichasayo. Ngokwezifundo zeklinikhi, enye yezilwanyana ezinobungcali nezikhuselekileyo zengcinezelo ziyi-tablet yeLizinopril.
Imiqondiso yokusetyenziswa kwamacwecwe eLizinopril
Isilwanyana sinconywa kwezi zilandelayo:
- Uxinzelelo lwe-arterial (njenge-arhente yokuzimela ezizimeleyo okanye ukudibanisa nezinye iziyobisi ezichasayo);
- ukuhluleka kwentliziyo engapheliyo (ekuhlaleni izigulane ezithatha i-cardiac glycosides kunye ne-diuretics);
- i-myocardial infarction (unyango lokuqala ngosuku lokuqala kwizigulane ezinemigangatho ye-hemodynamic ezinzileyo ukugcina le parameters, kwakunye nokukhusela ukungasebenzi kwe-ventricular nokungasebenzi kwenhliziyo);
- isifo sofuzo lwesifo sikashukela (ukwehla kwi-albuminuria kwizigulane ezine-type 1 zesifo sikashukela esifana nexinzelelo lwegazi kunye nezigulane ezine-type II yesifo sikashukela esinegazi eliphezulu).
Ukubunjwa kunye nesenzo samachiza se-lisinopril
Into esebenzayo yeziyobisi yenza i-lisinopril dihydrate. Izinto ezincedisayo zilandelayo: i-lactose, isitashi, i-silicon dioxide colloid, i-talc, i-stearate ye-magnesium, njl njl. I-Lizinopril ikhutshwa kwiipilisi ezi-5, 10 ne-20 mg.
Isiza lisiko kwiklasi ye-inhibitors ye-enzyme yokuguqula i-angiotensin (ACE inhibitors). Inikeza i-cardioprotective (ilungisa imeko esebenzayo ye-myocardium), i-vasodilator kunye ne-natriuretic (isusa i-sodium salts kunye nomchamo).
Isistim of lisinopril
Ngokwemiyalelo yokusetyenziswa, iipilisi ze-lisinopril zithathwa kanye ngosuku, kungakhathaliseki ukuba zithatha ukutya. Kucebise ukuba uthathe izilwanyana ngexesha elifanayo (mhlawumbi kusasa).
Isisombululo sincike kuhlobo lwe-pathology kwaye sinokumiselwa ngabanye ngedokotela. Ngoko, nge-blood pressure, i-dose yemihla ngemihla, njengomthetho, ngu-10 mg, kwaye umthamo wesondlo u-20 mg. Umthamo ophezulu ngosuku kufuneka ungadluli 40 mg. Ukuba ukuthatha i-Lisinopril kwi dose ephezulu ayiniki umphumo oyifunayo, kunokwenzeka ukunikezela unyango olongezelelweyo.
Ukuqapha
Ukungqinelana nokusetyenziswa kwe-lisinopril:
- i-edema idiopathic i-edema, i-edema kaQuincke ;
- angioedema kwimbali;
- ukukhulelwa kunye nokuhlaselwa;
- ukunyanzelwana kwamanye amayeza.
Ngoqaphele, le nkunkuma imiselwe kula maxesha alandelayo:
- isicic heart disease;
- ukungafezeki kolononari;
- izifo eziphazamisayo;
- i-collagenoses (kuquka i-systemic lupus erythematosus, scleroderma);
- i-hyperkalemia okanye ingozi eyongeziweyo yokuvela kwayo (kunye nesifo sikashukela, ukusetyenziswa ngokufanayo ngexesha lokusebenzisa i-diuretics, ukungaphumeleli kwe-renal);
- hyponatremia okanye isithintelo sodium kwisondlo;
- hyperuricemia;
- ukutshintshwa kweentso zenyuka;
- ubudala, njl
Imiphumo emibi ye-lisinopril:
- intloko, isisu;
- izifo zokulala;
- tachycardia;
- i-cardiac arrhymia;
- hypotension;
- ukunciphisa i-hemoglobin kunye ne-hematocrit;
- ukukhwehlela;
- isicupunu, ukuhlanza;
- isifo sohudo;
- umsebenzi wokuguguqula;
- ukugqithisa isikhumba, njl
Ngethuba loko unyango kunye ne-lisinopril kufuneka lijonge rhoqo umsebenzi wesibindi, i-potassium kunye nezinye i-electrolytes kwi-serum yegazi, igazi lekliniki.