I-Rheumatoid Arthritis - Izizathu kunye noPhathwe lwe-Inflammation Joint

Oogqirha be-rheumatoid arthritis babhekisela kwizifo ezingapheliyo, apho iingxube ezincinci zihlupheka. Kukholelwa ukuba lesi sifo sizenzekelayo - umzimba uyazibhubhisa izicubu zaso ngenxa yokungasebenzi kakuhle kwinkqubo yokukhusela.

Iimbangela ze-rheumatoid arthritis

Ukukhangela izizathu zesifo se-rheumatoid arthritis kuye kwaqhutywa oogqirha ngamashumi eminyaka. Kukho iimpawu ezininzi eziqinisekisa ubungqina obusulelayo besifo:

• qa qa qalisa;
• ukukhupha;
• ukwanda kweqondo lokushisa;
• ukuvuvukala kwama-lymph nodes.

Ukusuka kwenye imbono, ezininzi izinto zibonisa ukuba i-rheumatoid arthritis ayiyisifo esithathelwanayo:

• kwenzeka ngaphandle kokuxhomekeka kwexesha (nangona kukho umnxibelelwano wemozulu);
• ayikho iimeko zokudluliselwa ngegazi kunye nokufakelwa komzimba;
• Akukho phuculo kwipilisi kunye namachiza okulwa neyeza.

Izizathu ezichazwe ngasentla zikholisa oogqirha ukuba izinto ezithetha ngentsholongwane yesifo eso zibonisa umzabalazo wokuzikhusela ngomzimba wakhe. Inkqubo yokukhusela isonakalisa izicubu ezinxibelelwano zamalungu kunye nezinye izitho, zibabona njengabafokazi. Kuye kwabonakaliswa ukuba isibalo sezifo ezithathelwanayo sinokunyusa umngcipheko we-rheumatoid arthritis, phakathi kwabo;

• rubella ;
• herpes;
• I-Epstein-Barr virus ;
• i-hepatitis B kunye nabanye.

Imfuyo ye-genetic to the fact that rheumatoid arthritis iya kwenzeka kumntu othile incinci, kodwa ikhona. Iingcali zenzululwazi sele zifumene iizakhi ezikhethekileyo, njengokuba, umzekelo, i-DRB1, eguqula i-receptors kwiindawo zeembrane zeseli. Ngenxa yoko, i-immune system ayiqapheli iiseli zomzimba wayo kwaye ifuna ukuyichitha.

Kwimichiza, kukho umbandela we-rheumatoid factor. Le yimihlobo ye-antibodies ephikisana ne-immunoglobulin G. Lo mzimba-mzimba uveliswa ngamaseli afaka ngaphakathi ngaphakathi. Ama-antibodies kunye ne-immunoglobulin G yinto enzima eyenza ukuvuvukala okonakalisa izicubu ezidibeneyo. Ubukho bezinto zesifo se-rheumatoid emzimbeni kungabonakali nje ngesifo se-rheumatoid arthritis, kodwa nangenxa yokuba umntu osandul 'ukufumana isifo esithathelwanayo.

Ezinye izinto ezibangela ukubonakala kwe-rheumatoid arthritis:

• ukungenelela;
• nzakala;
• kubanda;
• uxinzelelo;
• utyhefu;
• ukukhulelwa, ukuhlambalaza, ukuphuma kwesikhashana;
• ukutya kokutya.

I-rheumatoid arthritis yintsholongwane yindlela yesifo esifana nabantwana kunye nabaselula. Olu hlobo lwe-arthritis lubonakaliswe ngento yokuba kungekhona nje kuphela amancinci kodwa amaninzi amaninzi ahluphekayo, kunye nezinye izitho zangaphakathi - iintso, intliziyo, imiphunga. Ukuvela kwesifo esibi kunokukhupha izinto ezininzi:

• bafumana usulelo olunzulu;
• ngxakini;
• i-supercooling;
• iilenki zamalungiselelo e-collagen;
• imfuza;
• ukukhulelwa komzimba okanye ukufumana i-immunodeficiency.

I-rheumatoid arthritis - iimpawu

Ukuqwalasela iimpawu zesifo se-rheumatoid arthritis, kufuneka kuthathelwe ingqalelo ukuba akukhona nje amajoyina, kodwa kunye neenkqubo ezipheleleyo zendalo zingathinteka. Uphawu oluphambili lwesifo lubuhlungu kumalungu, i-spectrum yayo isuka kumsindo kuya kwixesha eliqhelekileyo, rhoqo okanye ixesha elide. Esi sifo siqala ngamalungu ezandla, iinyawo, amadolo, iindlovu, ininzi echaphazelekayo. Ukongeza kwintlungu edibeneyo, kukho ukuvuvukala, okunciphisa kunye nokusetyenziswa kwezidakamizwa ezichasayo. Esi sifo esiqinileyo, amanxeba ayahluma, adibanise, aze ahlambe. Ngentsasa, isigulane sihamba ngokukhawuleza.

I-arthritis yabantwana iqala ngokuvuvukala nokuvuvukala kwamalungu amaninzi - idolo, i-hip, i-ankle. Esi sifo sihamba kunye nomkhuhlane, i-polymorphous rash (ngexesha lomkhuhlane), i-hepatolienna syndrome, i-lymphadenopathy, izitho zangaphakathi. Imisipha edibeneyo kumalungu afanelekileyo ahlaselwa. Ikhumba kwindawo yokuxhamla i-joints iba yincinci. Iindawo ezithethwa ngamathambo zinokuthi zidibanise kwaye zenze i-complex edibeneyo, oku kubizwa ngokuba yi-ankylosis.

Ngomonakalo wentliziyo kunye ne-arthritis yabantwana, i-amyloidosis iyaqala, ekhokelela ekuphelelweni kwezintso. Isibonakaliso somonakalo wezintso ngumprotheyini kumchamo, ukuvuvukala, ukuqokelela kwimisipha yerea. Ukuba isifo sichaphazela intliziyo, i-rheumatoid arthritis yintsholongwane iyinkimbinkimbi yi-myocarditis okanye i- pericarditis . Xa izilonda zamaphaphu zenzeka i-pleurisy okanye i-sclerosing alveolitis. I-Hepatolienal syndrome izimisele ngokunyuka kwesibindi kunye nesantya. Nge-lymphadenopathy, i-lymph nodes kwindawo yokwanda ehlangeneyo.

I-rheumatoid arthritis - iimpawu zokuqala

Kwi-90% yamatyala, amaqela ezandla aqala ukuhlaselwa. Xa ufumene i-rheumatoid arthritis yezandla, ukubonakala kweempawu zokuqala kunokwenzeka kakhulu kwixesha elibandayo. Ngexesha elide, ukuya kutsho umfanekiso ocacileyo wokuvuvukala kwamalungu, ubuthathaka, ukujuluka, ukulahleka kwesisindo, ubuhlungu besisu, imfucuza yomzimba kunye neerameter parameters zigcinwa kwizigulane.

I-rheumatoid arthritis yeminwe - iimpawu zokuqala:

• Ukuhamba kuphulwa, ukuvakalelwa kweentlungu kubonakala, ubomvu kunye nokuvuvukala kubonakala, ukushisa kuma-interphalangeal joints increases;
• iimpawu zivela kumacandelo e-metacarpophalangeal, ngoko kuhlanganiswa kwamanxeba;
• isigulane asikwazi ukulufaka isandla sakhe kwisibindi;
• iqala ukuvuvukala kweetoni ze-muscle.

I-rheumatoid arthritis - degree

Kwiyeza leyeza, ezine degrees okanye izigaba ze-rheumatoid arthritis ziyahluka:

1. Iyokuqala ibonakaliswa ngokucuthwa kwamathambo kwindawo edibeneyo, umonakalo kwizihlanganisi zezandla, ukuthambisa izithako ezidibeneyo kunye nesigaba sokuqala se-osteoporosis, ngelo xesha i-cysts kwiithambo zethambo ziqala ukwenza, esi sifo sisoloko singabonakaliyo okanye sineempawu ezinzima.
2. Okwesibini kukuphuhliswa kwe-tissu ye-bone tissue, i-cartilages iqala ukuguqulwa, ukuhamba kwamalungu amaninzi amakhulu kunciphisa, i-edema kunye nobomvu kubonakala kwiindawo ezichaphazelekayo, i-syndrome yesifo iyanokuthi ingabonakaliswa.
3. Okwesithathu - izicubu zethambo zincinci kakhulu, ukukhula kwezicubu ezinxibelelwano zikhawulezileyo, ukuhamba kwamalungu kunokukhawulelana, kwaye i-deposit deposits ivela.
4. Okwesine , i- osteoporosis enamandla ikhula, i-orooporosis eninzi iqhutyelwa, ininzi ye-tissue, i-ankylosis yamadolo, iigxala, izixhamlo ze-hip iyenzeka, imisipha i-atrophied kunye nezicubu eziluhlaza zombutho zidibene ngokupheleleyo.

I-rheumatoid arthritis - ukuxilongwa

Ukugqithisa ukuhlalutya kwi-arthritis ye-rheumatoyidala kuqala ngokuhlalutya ngokubanzi kunye nokuhlaziywa kwezinto eziphilayo zegazi ezibonisa umfanekiso wokuphuhlisa inkqubo:

• ukunciphisa i-hemoglobin (i-norm 120-160 g / l), ukwanda kwinani leukocytes (4000-9000 nganye ml yegazi) kunye ne-ESR (2-15 mm / h);
• ukwanda kwe-fibrinogen (2-4 g / l), iprotheni esebenzayo yeC-(engaphantsi kwe-5 mg / l), i-acal siali (620-730 mg / l okanye i-2-2.36 mmol / l), haptoglobin (0.44-3 , 03 g / l).

Ukuba i-arthritis ekhankanywe ngamathambo i-arthritis imiselwe:

• uphando lwe-rheumatoid yegazi;
• ukuhlalutya kwe-synovial fluid (imixholo yesigxina esivumeleneyo);
• i-arthroscopy - uviwo oludibeneyo usebenzisa isicatshulwa;
• i-radiographie, i- scintigraphy , i-imagination magontic resonance, i-ultrasound yesigulane.

I-ACCP kwi-rheumatoid arthritis iyinto evamile

I-Citrulin yi-amino acid ebonisa ukutshabalala. Umzimba uyazibona iiprotheni kunye neefom zengqungquthela ezenza iinkqubo ezizimele. Isifundo sokuba nobukho be-anti-citrulline-antibodies - I-ATSTSP ene-rheumatoid arthritis - yenye yeyona ndlela ibonisa kakhulu kwisigaba sokuqala. Ngokuxilongwa kwangaphambili kwesi sifo, uvavanyo luyinyaniso kuma 90-98 ekhulwini. Umgangatho oqhelekileyo we-ATSTSP - 3,0-3,1 U / ml, ukuguquka okuncinci kunokwenzeka ngokuxhomekeke kwiminyaka yobudala kunye nesondo.

Isifo se-rheumatoid arthritis

Phantse iipesenti ezingama-20 zezigulane zifumene i-arthritis ye-rheumatoid (i-seronegative) ene-negative rheumatoid ye-25-30 IU nge-milliliter yegazi. Olu hlobo lwesifo lunobungqina obuhle, kodwa luya kuba lubi ngakumbi kunyango oluyintloko, olufuna ugqirha ukuba akhethe imithi nganye. Ekubeni iziphumo zokuvavanywa ngamanga ngezinye izihlandlo zidibana nazo, kufuneka ukuba zithathe amaxesha amaninzi.

Isifo se-rheumatoid arthritis

Kwiimeko ezininzi, isifo se-rheumatoid arthritis sihamba kunye nesalathisi esihle se-rheumatoid factor - ngaphezu kwe-25 IU nge-milliliter yegazi. Olu hlobo lwesifo luyafana. Ephakamileyo isalathisi, ngokungekho mthethweni ukuhlaselwa kwesi sifo. Ukukhula kwento kungabangelwa kuphela yi-arthritis ye-rheumatoid, kodwa kunye nesifo esithathelwanayo, ngoko ke kuyimfuneko ukuqwalasela ezinye iinkqubo.

I-rheumatoid arthritis - unyango

Ukususela kwikhono logqirha oya kuthatha isigqibo malunga nendlela yokuphatha i-rheumatoid arthritis, umgangatho wesigulane wobomi kunye nobude bawo buxhomekeka. Ubungakanani besifo sifuna isigulane ukuba singabi nciphisa intlungu kwaye sifumane uncedo lwezokwelapha ngokukhawuleza, kwaye ugqirha ukuba uqhube uphando olubanzi ukufumanisa isigaba sesifo kunye nokunyanga okufanelekileyo.

I-rheumatoid arthritis - unyango, iziyobisi

Ukulungiselela i-rheumatoid arthritis yenza imisebenzi emibini:

• kwisigaba esichukumisayo - misa isifo;
• emva kokunciphisa ukukhushulwa - kunesiphumo sokuxhasa.

Xa unyango lwe-rheumatoid arthritis luyenziwa, izidakamizwa ezitsha zonyango ziyanciphisa iimpawu kwaye zinceda ukumisa isigulo:

• okuchasayo (nonsteroidal) - i-Ibuprofen, iDiclofenac , i-Meloxicam - imiselwe kwisigaba esicacileyo sokunciphisa isifo sesifo, ukuqina;
• i-glucocorticoids - i- Prednisolone , i-Methylprednisolone - inciphisa ukuvuvukala kunye nentlungu, ukunciphisa iinkqubo ze-pathological in the joints;
• i-antimetabolites - Azathioprin, i- Methotrexate - iyancipha iinkqubo eziyingozi kwi-arthritis yesifo se-rheumatoid;
• i-immunosuppressants - iCiclosporin, i-Penicillamine - unyango lwe-rheumatoid arthritis isetyenziselwa unyango oluhlangeneyo kunye ne-antimetabolites.

I-rheumatoid arthritis - unyango kunye nezilwanyana zabantu

Ukuxilongwa kwe-rheumatoid arthritis yeminwe kunye namanye amalunga kudinga ukusetyenziswa nje kuphela kwonyango oluqhelekileyo lweziyobisi, kuyinqweneleka kwaye kusetyenziswe izilungiso zendoda ezinceda ukunciphisa intlungu nokuvuvukala.

1. Ukugqitywa kwewayini ebomvu. Iwayini kufuneka ifudumale, igxinwe nge-gauze kwaye icindezele ngokudibeneyo imizuzu eyi-15.
2. Umhluzi we-laurel. I-tablespoon yezinto eziluhlaza kufuneka ibiliswe kwi-200 ml yamanzi imizuzu eyi-10, umhluzi kufuneka ungeniswe kwiiyure eziyi-8. Phuza 70 ml kathathu ngosuku ngaphambi kokutya.
3. I-ointment esuka kwipoward yompu. Hlanganisa i powderard, ioli yemifino kunye nobusi ngokulinganayo kwimizimba efanayo. Faka isicelo samafutha edibeneyo kwaye uyifake.

Isondlo se-rheumatoid arthritis

Ukutya okunzulu kwi-rheumatoid arthritis kuyimfuneko ukunciphisa izinga lokuphuhliswa kwesifo. Iibhunga lezondlo zeso sifo:

1. Ukubandakanya kwiintlanzi ezidityanisiweyo zentlanzi, ezizalisa ama-amino acids amanqindi, ukunciphisa ukuguqulwa kwamalungu.
2. Ukutya ilayisi ephekiweyo - isusa i-salts engaphezulu kunye nezinye izinto eziyingozi.
3. Ukunciphisa inani le-carbohydrates, i-spicy, ethosiweyo, amafutha ezilwanyana, ukutya okusemathinini-oku kuya kunceda ukunciphisa ubunzima, isonka esivela kwisonka esipheleleyo siyavunyelwa.
4. Ukunciphisa ityuwa, ukuze kungaphantsi kwe-body.
5. Ukwandisa inani lemifuno nezithelo (ngaphandle kweetatata, ii-eggplants), ngakumbi i-carotenoids - izaqathe, ingqolowa, ii-oranges, i-apricot.

I-rheumatoid arthritis - i-prognosis

Ukuba ulandela iziphakamiso zogqirha, landela ukutya kwaye ugcine indlela yokuphila enempilo - ukugxekwa kwesigulane kunokuthi kulungile. Ewe, i-rheumatoid arthritis yonyawo, izandla kunye namanye amalunga iya kuqhubeka ukuwachitha, kodwa kunengqiqo ukufezekisa ukuxolelwa. Kubaluleke kakhulu ukuba ungangcolisi impilo yakho, ngoko kufuneka:

1. Ukunciphisa utywala kunye ne-nicotine.
2. Ukunciphisa umzimba.
3. Gwema izifo ezithathelwanayo kunye ne-hypothermia.
4. Ukuphumla ngexesha.
5. Ukubhukuda, i-gymnastics, ukuhamba.