Xa unyango lwezifo ezibangelwa yi-microbial Klebsiellae pneumoniae, i-bacteriophage Klebsiella ehlambulukileyo isetyenziswa rhoqo. Olu lungiso lufumaneka ngesimo sesisombululo samanzi, esineendlela ezahlukeneyo zokusetyenziswa. Njengoko uqeqesho lubonisa, ukuphumelela kwesilwanyana kufana nokuthelekiswa kwamachiza omzimba.
Yintoni i-bacteriophage yashiya i-Klebsiella pneumonia?
Isithako esisisiseko sesisombululo si-phagolysates yebhaktheriya, eziyimveliso yokuchithwa kwee-microorganisms. Xa i-bacteriophage ingena kwiiseli ze-pathogenic, i-microbial lysis (dissolution) ivela, kwaye ngenxa yoko, ifa ngokukhawuleza.
Njengomlondolozo kwimveliso yeziyobisi ezisetyenziselwa i-quinazole. Ingcamango yayo iphantsi (ngaphakathi kwe-0.1 mg / ml) kwaye ayichaphazeli iimpawu zonyango zesisombululo seziyobisi.
Izibonakaliso zokuqeshwa kwebhakteriophage ecocekileyo yeKlebsiella pneumonia
Isilwanyana sisetyenziselwa ukuphathwa kwezi zifo zilandelayo:
- cholecystitis ;
- emathunjini amathumbu;
- gastroenterocolitis;
- pancreatitis;
- ulwasulelo lwe-urogenital;
- ukuxhaswa kunye neelonda
- peritonitis;
- i-colpitis;
- utyholongwane;
- pyelonephritis;
- bartholinite;
- i-salpingo-oophoritis;
- endometritis;
- omphalitis;
- i-cystitis;
- pyoderma;
- rhinoscleroma;
- ozena;
- osteomyelitis;
- imastitis;
- ikhefu;
- sepsis .
I-bacteriophage klebsiella isinconywa malunga neenkqubo zesifo kunye neendawo zangasese ekusebenziseni i-ophthalmic ezibangelwa yi-bhakteriyo, kuquka ne-nosocomial strains.
Imiyalelo yokusetyenziswa kwe-bacteriophage Klebsiella ehlambulukileyo
Isisombululo sinokusetyenziswa ngeendlela ezahlukeneyo, kuxhomekeke kwisifo esibangelwa yi-microorganism.
Isicelo sangaphakathi kwizifo zesisu esiswini sinokungena kweeyure ezingama-30 kwi-bacteriophage imizuzu engama-60 ngaphambi kokutya. Le khosi iintsuku ezingama-7.
Nge-pyelonephritis kunye ne-cystitis, ixesha le -rapy ye-systemic liyi-10-20 iintsuku, i-dosage ifanayo. Kufuneka uphinde usonge isisombululo sendawo kwisitya (20-50 ml) kunye ne-pelal pelvis (5-7 ml) nge-nephro- okanye cystostomy.
Ukunyanga i-purulent, iipilisi eziphilisa kakubi, izibhanki, ukunkcenkceshela, izicelo kunye ne-drainage ye-bacteriophage (ubuncinane kanye kanye ngosuku) isetyenziswa. Emva kokuvula i-abscess kunye nokususa i-exudate, iyeza lizaliswe ngesigxina (isixa sincinci kunomthamo wokupheliswa kwe-pus). Ngoxa uncedo lwamanzi, u-20-200 ml weziyobisi ulawulwa nganye iiyure ezingama-24. Ukuba amanxeba avela ngenxa ye-osteomyelitis, i-dose ephakanyisiweyo yokuhambisa amanzi i-10-30 ml, kunye ne-turundum ingasetyenziselwa.
Ukunyangwa kwezifo ezivuthayo zesifo se-gynecological kubandakanya ukulawulwa kwansuku zonke kwe-5-10 ml yesilwanyana kwisibeleko nasesiswini (1 ixesha ngosuku). Inkqubo yeyeza ihlala kwiintsuku ezi-14-15.
Ngezifo ezihlambulukileyo zendlela yokuphefumula nangaphezulu, i-bacteriophage ithathwa ngaphakathi (ukulinganisa kunye nendlela yokusetyenziswa kuyafana nokunyanga kwezilwanyana zesisu) kunye nesisombululo njengesisombululo
Ukugqabhuka ngokugqithiseleyo kwamathumbu kuvumela ukuba kusetyenziswe i-bacteriophage. Ukwenza oku, 1 ixesha ngosuku ubeka i-enema (40-50 ml yeyeza). Ulwaphulo lwengingqi kufuneka ludibene kunye neyeza zangaphakathi (amaxesha amabini ama-24 iiyure).
Nangona kungabikho kwemiphumo emibi, kunye nokuchasene nokutyunjwa kwamachiza achazwe, kubalulekile ukuhlalutya ubuchule bebhaktheriya kuyo ngaphambi kokuyisebenzisa.