I-Cordarone yamachiza kunye nayo yonke imiqondiso yayo kunye nokuchasene nokusetyenziswa kwayo yile iqela lezilwanyana ezichasene nezidakamizwa kwiklasi yesithathu. Oko kukuthi, isenzo saso sisekelwe ekukhuselweni kweziteshi ze potassium. Isilwayo sinempahla ye-antiarrhymics yeklasi yokuqala neyesine. Kwaye, ngokufanelekileyo, inokuthi ibambe izitishi ze-sodium ne-calcium ngokufanayo. Phakathi kwezinye izinto, le nkunkuma ine-beta-adrenergic block, i-anti-anginal kunye ne-coronary effects.
Imiqondiso yokusetyenziswa kwamacwecwe e-Kordaron
Isiseko sonyango si-amiodarone hydrochloride. Umlinganiselo osemgangathweni wesithako esisebenzayo ngu-200 mg. Ukongezelela kulo, ukulungiswa kokulungiselelo kufaka ezo zixhobo ezincedisayo:
- i-colylidal colloidal i-dioxide;
- lactose monohydrate;
- i-magnesium stearate;
- isitashi sommbila;
- Povidone.
Isixhobo seCordarone siboniswa ukuba sisebenzise zombini unyango kunye neenjongo zeprolactic. Yenza ngokuqhelekileyo kwi:
- i-tachycardias ehamba phambili yeparoxysmal;
- i-arrhythmias
- I-Wolff-Parkinson-White syndrome;
- i- extrasystole ;
- i-flutter yeeranti;
- tusycardia;
- ukubuyisela emva kokuphazamiseka kwe-myocardial;
- isigaba esichukumisayo se-myocardial infarction;
- fayili
- ukuphulwa kwemisebenzi ye-ventricle;
- isicic heart disease;
- ukuhlaselwa kwe-angina pectoris .
Indlela yokusebenzisa iipilisi ze-Kordaron zichongiwe ngugqirha oya kwiindawo. Iinkqubo ezahlukeneyo zonyango zingasetyenziselwa unyango. Ngoko, umzekelo, kwisilungiselelo sokugula, i-dose yokuqala ye-600-800 mg ye-amiodarone i-hydrochloride, yahlula ngamanani amaninzi. Umlinganiselo ophezulu ovumelekileyo wemihla ngemihla yi-10 g. Yaye le nyango ihlala kwiintsuku ezintlanu ukuya kwezi-ezisibhozo.
Iskimu sokuphulukiswa kwabagulayo siyafana, kodwa kufuneka sihlale ixesha elide - ukusuka kwiintsuku ezilishumi ukuya kwiiveki ezimbini. Kubalulekile ukukhumbula ukuba ubude bemizuzu engama-Kordaron abude kakhulu, ngoko kuyacetyiswa ukuba ukuyisebenzise yonke imihla. Ungaphinde uphuze amacwecwe ngamancinane - ukuya kwiintsuku ezimbalwa - ukuphazamiseka.
Qalisa unyango zonke iingcali zincoma ngeqondo eliphantsi kwaye zijolise kwifuthe eliyiphumo lokuphulukisa. Ukuba lo mva awunelisekile, ke umlinganiselo kufuneka wonyuswe.
Ukungqinelana nokusetyenziswa kweCordarone
Ukuchasana phantse nawaphi na amayeza. Kwaye uCordaron wayengenalo. Akukhuthazwa ukuba uphathwe nale nkunkuma ye-antiarrhymic xa:
- ukuchithwa komzimba kumacandelo okwakhiwa;
- Ukongezwa kwexesha le-QT (kokubili kokuzalwa kunye nokufumana);
- sinus bradycardia;
- ukukhutshwa komzimba;
- khulelwa;
- kuncelisa;
- isifo somphunga phakathi;
- hypokalemia;
- hypomagnesemia;
- iidyroid (i-hyper- okanye hypothyroidism);
- i-atrioventicular ivaliwe ukusuka kwinqanaba lokuqala ukuya kwisithathu.
Abantwana akufanele baphuze iipilisi ngaphambi kwelishumi elinesibhozo. Ngokuqaphelisisa, iCordarone kufuneka ilawulwe kwizigulane ezi:
- i-hypotension;
- ukuhluleka kwentliziyo engapheliyo;
- tshutshiswa kwemizimba;
- i-asthma ye-bronchial;
- i-cardiomyopathy;
- ukungazinzi.
Thatha amachiza phantsi kolawulo lweengcali, kunye nezigulane ezisebekhulile umzimba wazo unobuthakathaka ngenxa yenguqu ehambelana neminyaka kwaye unobungozi.
Kuyinto engathandekiyo ukudibanisa iCordarone ngamayeza anjalo:
- Quinidine;
- Mefelohin;
- Quinine;
- Pimozide;
- Fluphenazine;
- I-Spiramycin;
- IMisolastine;
- Sultopride;
- Terfenadine;
- Haloperidol;
- Bretilia;
- Sotalol;
- I-Spiramycin;
- Chlorpromazine;
- Ciammazine.