Isifo Sjogren's syndrome kubhekisela kwizifo ezizimelayo ezichaphazela izicubu ezinxibelelwano zezigulane ezifihlakeleyo - ngokugqithiseleyo zithende kwaye zihlasele.
Njengezinye izifo ezizimele, isifo sikaSjogren sisimo senkqubo. Yona ixhaphake phakathi kwezi zifo ezichaphazela izicubu ezixhumeneyo.
Kwiqela elisengozini yesi sifo, abafazi bahlala kwindawo ekhethekileyo, abafumana isifo seSjogren ngamaxesha angama-20 ngokuphindaphindiweyo kunamadoda. Iminyaka yobudala kule meko ayinandaba - lesi sifo sinokuvela kwixesha elivela kwi-20 ukuya kwiminyaka engama-60.
Izizathu zesifo sikaSjogren
Namhlanje, i-immunology ingenye yeendawo ezingenakucatshulwa zonyango. Njengoko iinjongo ezizenzekelayo zenze ukuba kuphuhliswe kwesifo sikaSjogren, oogqirha abanakho ukuphendula ngokungaqinisekanga oko kubangela ukuba sisifo. Kuyaziwa kuphela ukuba i-T-lymphocytes kunye ne-B-lymphocyte zifunyenwe kwizilonda zesifo ngexesha loviwo. Inani elikhulu le-immunoglobulins liyabonwa kwakhona. Oku kuphakamisa ukuba ii-superstressors zinciphisa, oko kuthetha ukuba iiseli ze-B ziyasebenza.
Kwizilingo zamagundane, izazinzulu ziye zafumanisa ukuba imbangela yokufa kwesi sifo sikaSjogren sinokwenzeka.
Izibonakaliso zesifo sikaSjogren
Isifo se-Sjogren sinokuphila okungapheliyo, ukuba okokuqala-kuphuhliswe ngaphandle kwemfuneko evela kwezinye izifo. Kukho nesifo sesibini seSjogren, kwaye kule meko ivela kwikhondo elide lezinye izifo - i-arthritis, i-lupus erythematosus, i-scleroderma, njl.
Uphawu oluphambili lwesifo ngumile weembrane. Ngenxa yokuba izigulane ezinamaqabunga kunye neziqhwala zihlala zichaphazelekayo, oogqirha bahlukanisa iimpawu ezimbini kwiimpawu:
- xerophthalmia - okuthiwa "iso elomileyo", apho amehlo avela efakwe. Ukuvutha komsindo kunye nesihlabathi;
- xerostomia - oko kuthiwa "umlomo owomileyo", okunciphisa i-salivation kwaye kukho stomatitis, caries, parotitis, "galling".
Njengoko isifo sifana nokukhula, sinokuchaphazela ezinye iindawo zomzimba:
- isikhumba esomileyo;
- ukubunjwa kwendlela ephakamileyo kwimpumlo;
- ukubetha kwisisu;
- tracheobronchitis;
- i-atrophic gastritis, i-biaryary dyskinesia, i-pancreatitis;
- glomerulonephritis ;
- Isifo sikaRaynaud;
- i-neuritis ye- facial and trigeminal nererve.
Ngokuqhelekileyo, izigulane zivakalelwa ngokukhawuleza ngamandla, kunye nentlungu kwiimisipha kunye namalungu.
Ukuxilongwa kwesifo sikaSjogren
Ukuze uhlolisise eso sifo, kufuneka usebenzise iindlela ezininzi:
- kwiprofayili kwiziko leenuclear
- Uvavanyo lukaSchirmer, oluvumela ukuvavanya ukusebenza kweengqungquthela ezilahlayo. Kule sifundo, umgca wephepha ubeka kwi-eyelidi ephantsi, kwaye emva kwesikhashana ubude beqela elixutywe kwiphepha lilinganiswa;
- i-sialometry - le ndlela igqiba ukuvalwa kwemali kunye ne-ascorbic acid;
- i-sialography - indlela esekelwe kwi-radiopaque, inceda ukuphanda i-partid salivary gland;
- Ukuhlolwa kwamehlo ngesibane sokubamba;
- I-biopsy yomlomo ichaza ukungena kweengqungqungquthela ze-salivary;
- I-US yemigulane ye-stali ivumela ukuba kugqitywe imeko yeengqungquthela ze-salivary kunye nobukho bamatye kwiindawo.
Ukunyangwa kwesifo sikaSjogren
Namhlanje, amayeza akanayo iindlela ezingasindisa umntu kwisifo sikaSjogren, ngoko ke, ngokwenene, unyango luyancitshiswa ekunciphiseni iimpawu.
Ngokomzekelo, amehlo angama-psy asetyenziswe iinyembezi zokufakelwa iimpawu - ezi zihlazo ezingenambala, ezifana nezo zomntu. Kwaye kufuneka kusetyenziswe amaxesha amaninzi ngemini ukukhusela ukoma kwe-mucosa.
Ngokutshatyalaliswa kweengqungqungquthela zogqirha, oogqirha babonelela izidakamizwa ezikhuthaza ukuphuma kwamathambo - enye yale myeza ibizwa ngokuba yiPilocarpine.
I-Corticosteroids isetyenziswe kwiimeko ezinzima xa iingxaki zikhokelela umngcipheko wokuthatha le mayeza.
Ukunyangwa kwesifo sikaSjogren kunye nezilwanyana zomntu
Iindlela zokulungisa izigulane nazo azikwazi ukuzisusa eso sifo, kwaye zingenza ubungozi obukhulu kumzimba.
Kukho indlela enye abantu abayisebenzisayo ukuphilisa isifo sika-Sjogren - iisenki ngeqanda elikhukhuni lekhukhu. Kubalulekile ukutshatyalaliswa kwintsholongwane yenkukhu entsha, bese uthatha ii-cubes ezingama-3 zeeprotheyini kwaye uzoncibiliza nge-saline ngemali efanayo. Umxube ujojowe nge-intramuscularly kwiibhokhwe 1 ixesha ngeveki ngenyanga 1. Le ndlela ingaba yingozi kakhulu ngenxa ye-salmonella.
Ngaphambi kokuba usebenzise le ndlela, khumbula ukuba ngaphandle kokuvunyelwa ngugqirha, ukuzinyango kungakhokelela kwizifo ezintsha.