I-Warfarin i-antiticoagulant yesenzo esingachangekanga, esivela kwi-coumarin. Isichengululo sithintela ubungqina besibindi sezinto ezixhomekeke kwi-vitamin-K. Ukuxinwa kwezi zinto kuyancitshiswa kwaye, ngokufanelekileyo, i-coagulability yegazi iyancipha. Isixa xa uthabatha iWarfarin kufuneka sibe nechanileyo. Ukongezelela, izigulana ezithatha le myeza zifuna iimvavanyo zegazi rhoqo ukuqinisekisa ukuba i-INR (isibalo segazi, esichaza i-coagulability yayo). Ukugqithisa okanye ukungafanelekanga kwe-warfarin kungabangela ukuphuma kwegazi kunye neminye imiba engaphantsi kwemiphumo eyahlukeneyo, ukuya kwisiphumo esibulalayo.
Iimpembelelo ezisemacaleni zeWarfarin
Ngexesha lokulawulwa kweziyobisi, ezi zilandelayo ziyakubonwa:
- Ukuhlamba - edla ukudibana nokusetyenziswa kwempembelelo yeCarfarin. Ngomzimba omncinci ungagqithiswa ngamagciwane egazi okanye ukubunjwa kweehematomas ezincinci esikhumbeni. Kwiimeko ezinqabileyo, i-anemia kunye ne-necrosis yendawo yesikhumba ngenxa ye-thrombosis ingenzeka. Ingaphakathi, kwaye ingakumbi isigulane esasongela ubomi isigulane sokungena kwemithi, ngokujonga ii-dose zokuthatha i-Warfarin, kubonakala malunga nama-1 angama-10 000 amacala, kwaye zihlala zidibaniswa nobukho bexinzelelo lwegazi kunye nezinye izidumbu.
- Ukususela kwinkqubo yokugaya ingabonwa isicongconi, isifo sohudo, ukuhlanza, iintlungu zesisu. Kwiimeko ezinqabileyo-uphuhliso lwe-jaundice.
- Kwinkalo yesantya, kwiimeko ezinqabileyo, kunokunyuka ukhathala, intloko, isisu, kunye nokuphazamiseka.
- Kwiimeko ezinqabileyo kakhulu ezinokuthatha ixesha elide kunye ne-warfarin, kukho iingxaki ezivela kwinkqubo yokuphefumula: i-tracheal okanye i-tracheo-bronchial calcification.
- Ngomntu ngamnye ogxekayo okanye ukunyamezela kweso sigqirha, ukugqithisa kwesikhumba, ukubetheka, i-dermatitis, i- vasculitis , i-alopecia (ukulahleka kweenwele) kunokubonwa.
Overdose Warfarin
Ukuphumelela unyango lweqondo leziyobisi kusekupheleni kwegazi, yingakho ukulawulwa kwe-INR kunye nokuthotyelwa kwamanyathelo afunekayo kunyango lwe-warfarin inendima enkulu enjalo. Ngeentsholongwane ezincinane, ngokuqhelekileyo isicatshulwa sinqanyulwa okanye umthamo wehlisiwe. Xa ukugqithisa ngokugqithiseleyo kuhambelana nokuphuhliswa kwegazi elininzi, sebenzisa i-vitamin K enomzimba (ukungathinteli umphumo we-Warfarin), kunye ne-plasma echanekileyo yegazi okanye i-coagulation factor concentrates.
Ulawulo lwe-INR xa uthatha iWarfarin
I-MNO i-standard standard standard, i-clotting factor, ebalwa ukusuka kwisiqulatho seprothrombin. Ngaphandle kwalesi sibonakaliso sisezantsi, igazi likhulu kwaye kukho ingozi enkulu yegazi. I-MNO ephezulu ibonisa umngcipheko wokuphuma kwamanzi. Kwinqanaba lokuqala, xa ukhetha umlinganiselo ofanelekileyo weziyobisi, isalathisi siyalinganiswa imihla ngemihla. Kwixesha elizayo kunconywa ukuba kuqhutywe uhlalutyo kanye ngeveki, kwaye ukuba ama-3-4 amanyathelo ahlala ngaphakathi kwimiqathango evumelekileyo, i-frequency ye-INR yesilingo inokunciphisa ibe kanye kwiiveki ezimbini. Uhlalutyo olongezelelweyo kwi-INR liyadingeka xa kukho utshintsho ekudleni, uxinzelelo, kunye nezinye izinto ezinokuchaphazela isibonakaliso.
Ukutya xa uthatha iWarfarin
Ukutya okunomlinganiselo omkhulu we-vitamin K kunokunciphisa ukusebenza kweziyobisi. Inani elikhulu le vithamini lifumaneka kwimifuno emitsha, ngoko kwonyango akufanele ihlaselwe yimveliso efana nale:
- avocado;
- iklabishi;
- anyanisi;
- cilantro;
- parsley;
- iikomkom (ngokukhethekileyo zicocwe, kuba i-vithamini ifunyaniswa kakhulu kwesikhumba), i-chicory;
- isinki;
- kiwi izithelo;
- isaladi;
- ioli;
- ipeysi;
- zesoya;
- pistachios;
- ezibomvu zolwandle;
- isipinashi.
Warfarin notywala
Utywala luphucula umonakalo we-antiticoagulant we-warfarin kwaye ngenxa yoko, ukuvela kwegazi elingenakwenzeka kungaqhutyelwa kwintlungu engaphantsi kwekhaya. Ukuthatha idosa enkulu yotywala kunye ne-warfarin kuqukunjiswe ukuphuhliswa kwamanzi angaphakathi, ngokuyinhloko kwisisu, esisongela ubomi.