Ama-enzyme e-proteolytic aphula izibophelelo ze-peptide kwiimodeli zeeprotheyini aze aphule iimveliso ze-molecular decay products. Xa uneminyaka yobudala, umzimba uvelisa ama-enzymes ambalwa. Ukongezelela, i-synthesis yabo ichaphazeleka kakhulu yizifo, izingozi zendalo kunye nezimo ezinqabileyo. Ngenxa yoko, ngamanye amaxesha azinako okwaneleyo emzimbeni.
Ukwahlula kweezymetic proteolytic
Ngaphandle kwama-enzymes e-proteolytic emathunjini, amaprotheni okutya aya kulungiswa kwaye aphethwe ngokukhawuleza. Zonke ezi zinto zihlukaniswe zibe zimbini iintlobo:
- i-peptidase, ngokuchukumisa ikakhulu izibophelelo zep peptidi zangaphandle kwiipepptide kunye neeprotheni;
- iiprostinase, ngokukodwa i-hydrolyzing i-peptide bond bonds.
Iipeptidases ziquka i-enzyme ebaluleke kakhulu ye-proteolytic (i-chymosin, i-pepsin kunye ne-gastricin) kunye ne-enzymes echaphazelekayo kwisisu somzimba (umzekelo, i-trypsin, i-elastase, i-chymotrypsin) yokugaya isisu.
Iiprostinase ziyi-enzymes yamanzi emathumbu. Ziyakwazi ukuba yi-serine, i-threonine, i-aspartyl kunye ne-cysteine.
Ii-enzyme zeproteolytic kwiziyobisi
Ukuba ii-enzymes zemvelo ze-proteolytic azikwazi ukufumana iziyobisi ze-inhibitor. Namhlanje kwii-pharmacy kukho inani elikhulu lamachiza anjalo. Iimvelo zendalo ze-proteolytic ziyizinto ezisebenzayo kwizilungiso zokuzalisa isitokisi. Ezi zenzi-zenzi ze-enzymatic zisetyenziselwa ukulungisa iintlobo ezahlukahlukeneyo zenkqubo yokugaya inyama emathunjini amancinci kunye nokusebenza kakubi kwesisu.
Enye yeentlobo zamachiza eziqulethe ezi zine-enzyme zicatshulwa kwi-mucosa ye-gastric, apho i-substance esebenzayo ebonakalayo yi-pepsin:
- Abomin
- Acidinpepsin.
La mayeza aphula phantse zonke iiprotheni zendalo. Ngokuqhelekileyo zisetyenziselwa i-gastritis nge-acidity ephantsi, kodwa akufanele isetyenziswe ekunyangeni izifo zesisu kunye ne-acidity ephezulu.
Udidi lwesibini lwamayeza luyilungiselelo oluyinkimbinkimbi, oluqulethe i-proteolytic enzyme eziphambili zeepakreas zezilwanyana. Ezi ziyobisi zinceda ukunciphisa iimpawu ze-exocrine. Imiqondiso enjalo iquka:
- kunciphisa ukutya;
- ukugubha;
- isicefe
- i-amylorea;
- ukuguquka .
Amachiza amaninzi afumanekayo kwaye asebenzayo anama-enzyme anjalo:
- Pancreatin;
- Lycrase;
- Mezim ;
- Pankurmen;
- Umdla;
- Enzistal;
- Digestal;
- Acidin-pepsin.
I-proteolytic enzymes ekhatheni izifo ezahlukahlukeneyo
Ii-enzyme ze-proteolytic zisetyenziselwa kwiizinyo zamathambo, ukuhlinzwa kunye namanye amasebe eyeza. Into yokuba le ndlela ye-enzyme, ukwahlula iiprotheni eziqhelanisiweyo kwilonda, iyanqanda ngokupheleleyo imithombo yezinto zokutya, eyona nto ibangela ukutshabalalisa.
Ukulungiselela kunye ne-enzyme yeproteolytic (i-Trypsin, i-Chymotrypsin) isoloko isetyenziselwa ukuhlala kwindawo yamazinyo ikakhulukazi kwiinkqubo ezinonyango
I-ointment nama-enzyme e-proteolytic (umzekelo, i-Iruksol) ingasetyenziselwa ukwelashwa kwe-enzyme yendawo yamanxeba. Ukulungiselela okunjalo kudala imeko yokuhamba ngokukhawuleza kunye nokukhawuleza kweenkqubo zokubuyisela, oko kukuthi, nangona amanxeba aphantsi kwaye akhululekileyo aphilisa, okwenza uboya obunqambileyo obushushu. Kwakhona, loo mafutha angasetyenziswa ukuphatha izilonda ze-decubitus kunye nezilonda ze-trophic.