Isifo sikashukela sisifo esibangelisayo, ngoko kubalulekile ukuqonda, i-hemoglobin ye-glycosylated-yintoni le nqondiso kunye nendlela yokuchithwa ngokuchanekileyo olo hlalutyo. Iziphumo zinceda ugqirha ukuba agqibe ukuba umntu unesinga lesetyhukela yegazi okanye into eqhelekileyo, oko kukuthi, unempilo.
I-hemoglobin yeGlycosylated - yintoni na?
Ikhethwe iHbA1C. Esi sibonakaliso sezinto eziphilayo, iziphumo ezibonisa ukuxinwa kwe-glucose egazini. Ixesha elihlalutyiweyo iinyanga ezintathu zokugqibela. I-HbA1C ithathwa njengesicatshulwa esicacisa ngakumbi kune-hematest yesondlo. Isiphumo, esibonisa i-hemoglobin esine-glycated, iboniswe njengepesenti. Ubhekisela kwingxenye ye "iswekile" iimveliso kwi-volume epheleleyo yamaseli obomvu. Izalathisi eziphakamileyo zibonisa ukuba umntu unesifo sikashukela, ngaphezu koko, isifo sisimo esibi.
Uhlalutyo lwe-hemoglobin ye-glycosylated inezinzuzo ezininzi:
- Isifundo singaqhutyelwa ngaphandle kokubopha ixesha elithile lomhla, kwaye akunjalo kwisisu esingenanto;
- iziphumo zolu hlalutyo azichaphazelekayo zizifo ezithathelwanayo kunye nokunyuswa kwengcinezelo;
- Uphononongo olunjalo luvumela ukufumanisa kwangaphambili isifo sikashukela kunye nokuqaliswa kwonyango ngexesha elifanelekileyo;
- Uhlalutyo lunceda ukufikelela kwisigqibo malunga nokuphumelela kwonyango oluqhubekayo lwesifo sikashukela.
Nangona kunjalo, le ndlela yokuphanda iimpazamo ayikho into:
- Indleko ephezulu - inexabiso elikhulu xa kuthelekiswa nohlalutyo lokutyhila isalathisi;
- kwizinga eliphantsi le-hormone ye-thyroid, i-HbA1C iyanda, nangona kwimeko apha i-blood level ye-glucose level incinci;
- kwizigulane ezine-anemia, iziphumo ziphosakeleyo;
- ukuba umntu uthatha i-vitamin C no-E, umphumo uyinto encinci.
I-hemoglobin yeGlycosylated - njani ukuthatha?
Ama-laboratories amaninzi enza eso sifundo athathe iisampula zegazi kwisisu esingenalutho. Oku kwenza kube lula ukuba iingcali zenze uhlalutyo. Nangona ukutya akuphazamisi iziphumo, kodwa ukuba igazi alithathwa kwisisu esingenalutho, kufuneka uxelele. Uhlalutyo lwe-hemoglobin ye-glycosylated lungenziwa kwintombi kunye nomnwe (konke kuxhomekeke kumzekelo we-analyzer). Kwiimeko ezininzi, iziphumo zesifundo zilungele emva kweentsuku eziyi-3-4.
Ukuba phakathi kwemida yesiqhelo kukho isibonakaliso, uhlalutyo olulandelayo olunikezelayo lunokwenzeka kwiminyaka eyi-1-3. Xa isifo sikashukela sitholakala kuphela, isifundo sesibini sinconywa ezintandathu ezintandathu. Ukuba isiguli sele sise-akhawunti ye-endocrinologist kwaye imiselwe unyango, kuyacetyiswa ukuba uthathe uhlalutyo rhoqo kwiinyanga ezintathu. Uhlobo olunjalo luza kunika ulwazi ngenjongo malunga nemeko yomntu kunye nokuvavanya ukusebenza kwe-regimen yonyango.
Uhlalutyo lwe-hemoglobin ye-glycated-preparation
Olu phando luhlukile kwihlobo lwayo. Ukuze udlule ukuhlolwa kwegazi kwi-hemoglobin ye-glycosylated, akudingeki ulungiselele. Nangona kunjalo, ezi zinto zilandelayo zingaphazamisa umphumo (ukunciphisa):
- kuphuma;
- hemodialysis.
Uhlalutyo lwe-glycosylated (glycated) hemoglobin lungcono ukuthatha kwiibhubhoratri ezinezixhobo zanamhlanje. Siyabulela oku, umphumo uya kuba ochanekileyo. Kufuneka kuqatshelwe ukuba izifundo eziqhutywe kwiibhubhoratri ezahlukeneyo kwiimeko ezininzi zinika izibonakaliso ezahlukeneyo. Kungenxa yokuba iindlela ezahlukeneyo zokuxilonga zisetyenziselwa kumaziko ezonyango. Kuyinto enqwenelekayo ukuvavanya kwi-laboratory evavanyo.
Ukumisela kwe-hemoglobin ye-glycosylated
Kule mini, akukho mgangatho omnye ongasetyenziselwa ama-laboratories ezonyango. Incazelo ye-hemoglobin ye-glycosylated egazini yenziwa ngeendlela:
- chromatography yamanzi;
- immunoturbodimetry;
- i-chromatographic exchange exchange;
- uhlalutyo lwe-nephelometric.
I-hemoglobin yeGlycosylated iyinto evamile
Esi sibonakaliso asinalo ukuhlukahlukana kweminyaka yobudala okanye ngesondo. Isiqhelo se-hemoglobin ye-glycosylated egazini kubantu abadala kunye nabantwana iyamanyaniswa. Ihamba ukusuka kwi-4% ukuya kwi-6%. Iimpawu eziphakamileyo okanye ezantsi zibonisa i-pathology. Ukuba uhlalutya ngokukodwa, oku kukuthi i-hemoglobin ye-glycosylated ibonisa:
- Udidi lwe-HbA1C luvela kwi-4% ukuya kwi-5.7% - umntu ulungelelaniso lwe-carbohydrates metabolism. Ubunokwenzeka bokuhlakulela iswekile
- Isalathisi se-5.7% -6.0% - iziphumo ezinjalo zibonisa ukuba isigulane sinomngcipheko okhulayo wokugula . Unyango alufunanga, kodwa ugqirha uya kuncoma ukuba athathe ukutya okuncinane.
- Udidi lwe-HbA1C ukusuka kwi-6.1% ukuya kwi-6.4% - umngcipheko wokuba nesifo sikashukela sikhulu. Isigulane kufuneka sinciphise inani le-carbohydrates esetshenziswe ngokukhawuleza kwaye lihambelane nezinye iingcebiso zegqirha.
- Ukuba isibonakaliso si-6.5% - ukuhlola okokuqala "isifo sikashukela." Ukuyiqinisekisa, uviwo olongezelelweyo luqeshwe.
Ukuba uhlalutyo lwe-hemoglobin ye-glycosylated inikwe ngabafazi abakhulelweyo, umgangatho wolu hlobo ufana nalawo wonke umntu. Nangona kunjalo, esi sibonakaliso sinokuhluka ngexesha lonke lokubeleka komntwana. Izizathu ezivusa ukuqhuma okunjalo:
- i-anemia kubafazi ;
- Isiqhamo esikhulu kakhulu;
- iinjongo ezingasebenzi.
I-hemoglobin yeGlycosylated ephakamileyo
Ukuba esi sibonakaliso singaphezu kwesiqhelo, oku kubonisa iingxaki ezinzulu ezenzeka emzimbeni. I-hemoglobin ephezulu ye-glycosylated ihlala ihamba kunye neempawu:
- ukulahleka kombono;
- ukuphilisa ixesha elide lamanxeba;
- unxaniwe;
- ukuhla okubukhali okanye ukwandisa ubunzima;
- ukungonakaliswa kwe-immunity;
- ukukhawuleza ukuba ugonywe;
- ukubola nokulala;
- ukunyuka kwesibindi.
I-hemoglobin yeGlycosylated ngaphezu kwesiqhelo - ithetha ntoni?
Ukwanda kwoluphawu kubangelwa zezi zizathu zilandelayo:
- ukungaphumeleli kwi-carbohydrates metabolism;
- izinto ezingahambelani nezinga leswekile.
Igazi le-hemoglobin ye-glycosylated liza kubonisa ukuba lo mfanekiso ungaphezu kwesiqhelo, nantsi iimeko:
- kwi-diabetes mellitus - ngenxa yokuba inkqubo yokwahlula i-carbohydrates iyaphulwa kwaye izinga le-glucose landa;
- xa utyhefu ngotywala;
- ukuba isigulane esinesifo sikashukela sinokunyangwa ngokuchanekileyo unyango;
- ngenkunkuma ye-anemia;
- emva kokumpontshelwa igazi;
- kunye ne-uremia, xa kukho ukukhwa kwe-carbogemoglobin-into ebonakalayo efana neHbA1C;
- ukuba isigulane sinokususwa kwipeni - umzimba ojongene nokulahlwa kweeseli ezibomvu zegazi.
I-hemoglobin ye-Glycated iphakanyisiwe - yintoni endiyenzayo?
Ukumisela izinga leHbA1C liya kunceda ezi ngcebiso ezilandelayo:
- Ukucebisa ukutya kunye nezithelo kunye nemifuno, iintlanzi ezilumkileyo, i-legumes, i-yogurt. Kubalulekile ukunciphisa ukusetyenziswa kokutya okunamafutha, ukutya.
- Zikhusele ekucindezelekeni, okuchaphazela kakhulu imeko yomzimba.
- Ubuncinane isiqingatha seyure ngosuku ukubandakanya kwimfundo engokwenyama. Siyabulela oku, izinga le-hemoglobin ye-glycosylated iya kuncipha kwaye i-well-being iyakuphucula.
- Ukutyelela rhoqo ugqirha uze wenze zonke iimvavanyo ezimiselweyo.
I-hemoglobin yeGlycosylated iyancipha
Ukuba le nqondiso ingaphantsi kwesiqhelo, kuyingozi njengokwanda kwayo. I-hemoglobin ephantsi ye-glycosylated (ngaphantsi kwe-4%) ingacatshiswa yizinto ezilandelayo:
- ukulahleka kwegazi, okwakusandul 'ukugqithiswa;
- ukungasebenzi kwepascreas;
- i-hypoglycemia ;
- ukungabi namandla ;
- i-pathologies, apho kutshabalaliswa kwangaphambili kwe-erythrocytes.