Nangona ukungasebenzi kakubi kwi-thyroid gland kukhokelela kwimiphumo emibi yempilo. Iqondo le-TPO, i-enzyme, eveliswa yi-gland, ifundwa kwizifo ezininzi. Emzimbeni onempilo ezi zinto zingekho okanye inani labo liyancitshiswa, kodwa inani labo likhula ngezifo zokuzivikela, apho abantwana nabamabhinqa bahlala bejamelene nazo. Ukuxilongwa kwabasetyhini, kwanokuba ukuphambuka okuncinci kwii-antibodies ze-TPO kubalulekile.
Isantya se-antibodies kwi-TPO
Ukuvavanya imeko ye-thyroid, isigulane sinconywa ukuba sithathe uvavanyo. Njengempahla yokuvavanya, igazi elivela emthanjeni, elinikezwa kusasa kwisisu esingenalutho, lisetyenziswe. Iimpawu zolu vavanyo ziba ziimeko ezinjalo:
- ukucaciswa koxilongo lwe-hypothyroidism kunye ne-hyperthyroidism;
- goiter;
- ukuvuvuka kwemilenze;
- phambi kokumisela imishanguzo echaphazela i-thyroid gland;
- ekufundeni ukungabikho komntwana;
- izifo ezizimele (vasculitis, lupus, isifo sikashukela).
Xa ufunda i-antibodies kwi-thyroid peroxidase (TPO), isiqhelo sisuka kwi-0 ukuya kwi-35 U / L kubantu abangaphantsi kweminyaka engama-50 ubudala. Kubantu abangaphezu kwama-50 anxamnye ne-TPO kufuneka agcinwe ukusuka kwi-zero ukuya kwiiyunithi ezili-100 / ilitha.
Kubalulekile ukuba uqaphele ukuba malunga ne-10% yezigulane ezineengxaki ze-thyroid ziqulethwe ngumntu omncinci we-antibody. Oku kubonakala kakhulu kulabo bahlukunyezwa zizifo ze-rheumatic.
Ukuba ama-antibodies kwi-TPO aphezulu kuneqhelekileyo
Ukugqithisa isalathisi kunokwenzeka ngenxa yezinto ezinjalo:
- I-Hashimoto's thyroiditis (iimeko ezingama-90%), apho izikhuhlane ze-antibodies ziseli ye-thyroid;
- Isifo seMangcwaba ;
- hypothyroidism;
- Sesifo se Croven.
Kufuneka kuphawulwe kunye nezinto ezingathanga ngqo ezichaphazela i-TVET:
- zendalo ezimbi;
- uxinzelelo;
- umonakalo umonakalo kwi-thyroid;
- lonyango lwexesha elide ngeendlela ze-hormonal;
- izifo zentsholongwane.
Ukuba ii-antibodies ze-TPO zigqithise isiqhelo kumfazi kwisigaba sobunzima, umngcipheko we-thyroiditis emva kokunikezelwa kuphezulu. Ukongezelela, imeko efana nayo inokuchaphazela kakubi ukuphuhliswa komntwana. Ukwanda kwenani leengqungquthela luchazwa yi- hypothyroidism , eyona nto ibangela ukwanda kwama-hormone. Ingozi yalesi sifo kubantwana kukuba izayo iholele ekutheni i-cretinism.