I-progesterone ye-17-OH yinto ephakathi kokusebenzisana kwama- hormone weprogesterone kunye ne-17-hydroxyprepnenolone, kwaye inegama elipheleleyo le-hydroxyprogesterone. I-hormone emzimbeni womntu iveliswa ngama-adrenal glands, nakwabasetyhini kunye nama-ovaries, kunye ne-placenta ekukhutheni. I-progesterone ye-17-OH ithintela ithuba lokukhulelwa, inkqubo evamile yokukhulelwa kunye nophuhliso lomntwana. Ukungabikho kokukhulelwa, izinga le-hormone kumzimba wesifazane alibalulekanga kwaye lihluka ngokuxhomekeke kwisigaba sokuhamba kwimihla. Amanani aphakamileyo aphezulu kwixesha lokunyuka kwexesha, ngokuthe ngcembe kwehla ukuya ekuqaleni kwexesha.
Uhlalutya
Uvavanyo lwegazi malunga ne-17-OH progesterone imiselwe abo babini abasetyhini nabantwana. Kwimeko yokuqala, isibonakaliso sikrokrela isisu se-adrenal glands, ukungabikho komntwana, ukuphulwa komjikelezo wokuya esikhathini, okwesibini - ukufumanisa i-adrenogenital syndrome. Ukususela kwinjongo yokuhlalutya kuxhomekeke kwixesha lokuthatha i-progesterone ye-17-OH. Njengomthetho, abafazi bavavanywa i-progesterone 17-OH 3-4 iintsuku emva kokuqala kokuya esikhathini, abantwana - ekuseni ngesisu esingenalutho.
Uhlalutyo luphumo
Kukho iintlobo ezi-2 zokuhluka kweziphumo:
- Amanqanaba aphakanyisiweyo yehomoni abonisa ukuba izidumbu zamanqanda kunye neengqungquthela ze-adrenal. Kwakhona, i-progesterone ephakamileyo ye-17-OH yimbangela yokungena kwexesha lokungena kwexesha kunye nokungabikho komntwana. Kubantwana, izibonakaliso eziphakanyisiweyo zibonisa indlela yokuvelisa imfuyo echaphazelekayo ehambelana nokuveliswa kwemiphumo engafanelekanga.
- Inqanaba elinciphileyo lehomoni libonisa umsebenzi ongenamsebenzi wee-ovari okanye izifo ze-correx ye-adrenal. Kubalulekile ukuba uqaphele ukuba amanqanaba aphantsi e-hormone ayanciphisa kakhulu amathuba okukhulelwa, kwaye ngoko ke kufuneka ukuba kwenziwe utshintsho olufunekayo ngemveliso yonyango.