I-TTG - isiqhelo kubasetyhini, kuxhomekeke kwiminyaka yobudala, ixesha lomhla nomoya

Zonke iinkqubo ze-biological emzimbeni womntu zilawulwa ngama-hormone. Ezi zixhobo zamakhemikhali azichaphazeli nje kuphela umzimba, kodwa kwakhona ziimeko zengqondo, ngakumbi kubafazi. Nokuba ukuphambukiswa okuncinci kwe-balance-endocrine ukusuka kwinto eqhelekileyo kunokunyusa kakhulu imeko yezempilo kwaye kubangele iingxaki ezinzulu.

Ihomhoni ye-thyroid-stimulating hormone - yintoni le yabasetyhini?

Isicatshulwa esichazwayo senziwa kwi-pituitary gland yengqungquthela, ukugcinwa kwayo kulawulwa yinkqubo yesiseko senzwa (kakhulu inxalenye). I-hormone ye-TSH okanye i-thyrotropin yi-glycoprotein eneziphumo ezilandelayo kumzimba wesetyhini:

• ukulawula imveliso ye-T3 (triiodothyronine) kunye ne-T4 ( thyroxine );
• umgaqo wokujikeleza kwimizi, imisebenzi yokuzala kunye nesisu somzimba;
• Ukuqinisekisa ukulinganisela kwamandla omzimba;
• ukuthatha inxaxheba kwi-synthesis ye vithamini A, i-phospholipids, i-acide nucleic kunye neeprotheni;
• ukujongwa komsebenzi wezitho zamehlo, ukuva, iintliziyo zentliziyo kunye neentsholongwane;
• ukuphuculwa kwe-iodine ukufaniswa ngeeseli zegciwane ze-thyroid;
• ukuzinza kweempendulo ze-psychosomatic ukunyanzelisa.

Ngokuqhelekileyo, kukho ingxelo engalunganga T3, T4 kunye neTTG. Ngokunyuka okanye ukunyuka okubukhali kwi-concentration ye-triiodothyronine kunye ne-thyroxine kwi-plasma yegazi, i-thyroid gland ibonisa ukuba ungalingani. Ngenxa yoko, ubukhulu bemveliso ye-thyrotropin buyahluka, ngoko ke ukuxilongwa ngokuchanekileyo kuyimfuneko ukucacisa inani lala maqumrhu e-biological enzima.

Uhlalutyo lwe-hormone - iTTG

Ikhemikhali echaphazelekayo ibonakaliswa ukunyuka kwemihla ngemihla. Isixa sayo esiphezulu kwiplasma sibonwa phakathi kwama-2-4 iiyure zobusuku. Ngo-6-8 ekuseni, i-thyrotropin iqala ukuhla, ifikelela ephantsi ngokuhlwa, ngoko igazi kwi-TTG lungcono ukuthatha ekuseni. Ukuba uhlala uphapheme ebusuku, ukuveliswa kwe-hormone kunzima kakhulu.

Ukulungiselela ukuhanjiswa kwegazi kwi-TTG

Ukuchonga ngokuchanekileyo ukuxinwa kwe-thyrotropin, zonke iziphumo ezichaphazelekayo ezinokuchaphazela iziphumo zesifundo kufuneka zifakwe ngaphandle. Iingcaphephe zincoma ekuseni ukuba zithathe i-TTG - ukuhlolwa kwegazi kwiiyure zokuqala kuya kunceda ukuqikelela ixabiso elithembekileyo, kufuphi nobuninzi. Kubalulekile ukuba ubuthongo obuhle ngaphambi kokuya kwibhubhoratri, ngaphandle koko ukuthembeka kwesi sifundo kuya kuncipha.

Ngaphambi kokuba uthathe uvavanyo lwegazi kwi-TTG, kufuneka:

1. Ungadli iiyure eziyi-8.
2. Yeka ukutshaya ngosuku lokufunda.
3. Ngethuba lokutyelela kwibhubhoratri, khetha ukutya okulula ukugaya, kwaye ungadli kakuhle.
4. Gwema ukukhutshwa ngokomzimba nangokomzwelo.
5. Musa ukusela utywala iintsuku ezingama-5 phambi kohlalutyo.

I-hormone ye-thyrotropic iyaqhelekileyo kubafazi

Kwii-laboratories ezahlukileyo, ixabiso leparameter echaziweyo lixhomekeke kububungqina bezixhobo, ngoko ke kuyisiko ukubonisa izikhombisi zokubonisa. I-TTG - isiqhelo kubasetyhini ngama-age (mIU / l):

• 14-25 iminyaka - 0,6-4,5;
• 26-50 ubudala ubudala - 0.4-4.0;
• emva kweminyaka engama-51 - ukuya kwi-4,5.

Ingqalelo ekhethekileyo kwi-thyrotropin kufuneka inikwe abafazi, ifikelela kwiminyaka engama-40 ubudala. Eli thuba lidlulela ukuphela komntu, ngoko ke ukungafezeki kwe-hormonal kunye neengxaki ezinxulumene nazo. Emva kokumisa umva, kubalulekile ukuba iliso rhoqo kwinqanaba le-TSH - umgangatho wesi sikhombisi akufanele udlule kwimida ye-0.4-4.5 mIU / l. Ukwanda okanye ukunciphisa kwi-thyrotroprop isifo esiphezulu sezifo ze-thyroid kunye neenkqubo eziphilayo ezilawulayo.

I-TTG iphakanyiswa okanye ikhuliswa - ithetha ntoni kubafazi?

Ukunyuka kwexesha elilodwa kwinkxalabo yekhemikhali eyenziwe yicandelo lugqithiselwa oogqirha njengento eyahlukileyo yesiqhelo. I-hormone ye-thyroid-stimulating iphakanyiswa kwimida eyamkelekileyo malunga neemeko ezinjalo:

• ukungabikho kokulala;
• ngophaya;
• uxinezeleko okanye ukuvusa ingqondo;
• ukuphulwa kwemithetho yokulungiselela ukuhlalutya;
• ukusetyenziswa ngokugqithiseleyo kwe-iodine.

I-TTG iphakanyisiwe - izizathu

Ukuba i-thyrotropin e-plasma yegazi iphezulu kakhulu kuneyona evamile, kufuneka uqhagamshelane ne-endocrinologist. Ingcali kuphela iza kukwazi ukuba kutheni i-hormone ye-thyroid-stimulating iphakanyisiwe-oko kuthetha ukuthini, ayikwazi ukuchongwa ngesiseko seziphumo zohlalutyo olulodwa kunye nokuhlolwa komzimba. Ukuqaphela izizathu eziphambili zengxaki, kuya kufuneka uqhube uchungechunge lwezifundo uze ufumane i-T3 ne-T4.

Kukho iziganeko ezininzi zeempatho ezichaphazela i-hormone ye-thyroid-inokudlulela kwiimeko ezilandelayo:

• ukuvuvukala kwe-thyroid gland;
• hypothyroidism ;
• utyhefu kunye nezixhobo zokuhamba;
• Ukungaphumeleli kweengxowankulu eziphambili;
• ukugula kwengqondo;
• ukukhuseleka kwezicubu kwi-hormone ye-thyroid;
• iimvumba;
• gestosis ;
• ukuphazamiseka kwenkqubo ye-nervous central;
• Hashimoto's thyroiditis nabanye.

I-TTG iphakanyisiwe - unyango

Unyango lwengxaki lusekelwe kwingxelo engalunganga, edibanisa i-hormone ye-thyroid ne-thyroxine. Ukubuyisela imeko kwiimeko eziqhelekileyo kuya kwandisa ingxube ye-plasma ye-T4. Xa i-TSH iphakanyisiwe, i-endocrinologist ichaza ukuthatha imithi kunye nomxholo we-thyroxine. Isisombululo, ukusetyenziswa kwamanqanaba kunye nobude bonyango kubasetyhini kubalwa ngabanye. Amalungiselelo asebenzayo:

• Bagotiroks;
• Efanelekileyo;
• Euterox;
• Thyreotome;
• L-thyroxine kunye neempawu ezifanayo.

Ihomoni ye-thyroid-stimulating is down - ithetha ntoni?

Njengoko kwimeko yokwanda, ukunciphisa okuncane kumlinganiselo we-TSH akusengumqondiso onobungozi. Kubasetyhini, le ngxaki ngamanye amaxesha iyenzeka ngokuguquka kwimijikelezo yokuya esikhathini. I-TSH ephantsi njengento eyahlukileyo yinto eqhelekileyo ibonwa ngasemva kwezinye izinto:

• indlala okanye ukuthotyelwa kwesondlo esingqongqo ekulahlekeni kwesisindo;
• ukuthatha iziyobisi ezithintela i-thyroid gland;
• uxinzelelo kwixesha lokuhlalutya;
• Ukusetyenziswa kakubi kweziyobisi ze-hormonal.

I-TTG iyancipha - izizathu

Ukuba izinga lezinto eziphilayo liphantsi kakhulu kunesiqhelo, kubalulekile ukutyelela ugqirha ngokukhawuleza. Izifo kunye neemeko zempilo apho i-hormone evuselela i-thyroid iyancipha:

• izicubu ze-thyroid gland;
• encephalitis;
• I-Itenko-Cushing syndrome;
• i-meningitis;
• Izifo zeGrvs;
• Isifo seShihan;
• iipopoplasms in the gland gland;
• thyrotoxicosis;
• Isifo sePlummer;
• ukudandatheka kunye nabanye.

I-TTG iyancipha - unyango

Ukumisela umxholo we-thyrotropin kwi-plasma yegazi kuyimfuneko ukujamelana nesifo esisisigxina kwaye ngokufanayo nokusebenzisa i-hormone zokwenziwa. Inqanaba le-TSH lonyuswa ngamachiza akhethekileyo, anqunywe kuphela yi-endocrinologist ngokwalo:

• Parasosin;
• Amiodarone;
• Methimazole;
• I ipodeyt;
• Erythrosine kunye neempawu.

TTG ekukhulelweni

Ngomama ozayo, inkqubo ye-endocrine isebenza ngokungafaniyo, kuba ama-hormone yomntwana ayengakabonakali. Ukususela kwixesha lokunyuka kunye nenani leembrusi, ukuxinwa kwe-TSH - isiqhelo kubasetyhini abakulungele ukubukeka komntwana (mIU / l) kuya kuxhomekeka:

• 1 trimester - ukuya ku-0.4;
• 2 trimester - 0,3-2,8;
• 3 trimester - ukuya kwi-3,5.

Ngokukhawuleza emva kokukhulelwa, ukwehla okuthile kwi-thyrotropin kukuphawu. Oku kungenxa yokunyuka kwegazi kwi-thyroid gland, yingakho i-T3 kunye ne-T4 yokuvelisa isebenze. Ngokuchasene nempendulo engalunganga, ukwanda kwenkxalabo yabo kubangela ukunyanzeliswa kwemveliso ye-hormone echazwe. Ukuba kukho iintsholongwane ezininzi zesisu, esi sibonakaliso sinokulingana nesantya, eli lizwe lithathwa njengento ekhoyo.

Ukuba i-TTG iphakanyisiwe ekukhulelweni, kuyimfuneko ukudlulisa kwakhona uvavanyo kwaye u tyelele i-endocrinologist. Umthamo omkhulu we-thyrotropin unobungozi kumntwana kwaye kaninzi uphazamisa iingxaki zesigxina, ukuyeka ukuphuhliswa kwemibungu kunye nokulahlekelwa ngamathambo. Ukuqhelanisa izinga le-TSH kubasetyhini abakulungiselela ukubeleka, amayeza akhethekileyo ayalelwe:

• levothyroxine sodium;
• Bagotiroks;
• L-thyroxine;
• Tiro-4;
• L-Tirok kunye neempawu ezifanayo.