Ngokuqhelekileyo, abafazi abahlanjelwa kukuhlaselwa kweentloko ezinzima, bathatha i- analgesics , ezenza ukuba imeko ibe yinto ephuculisayo, kwaye ekugqibeleni bayeke ukunceda. I-Triptans esuka kwi-migraine iphumelela ngokwenene-iziyobisi ezicwangciswe ngokukodwa ukuphathwa kwesi sifo. Akhawulezi ngokukhawuleza ukukhulula intlungu yesifo, kodwa inokuthintela ukuphuhliswa kokuhlaselwa, ukuba uthatha imithi kunye neempawu zokuqala zokugula.
Izidakamizwa ezivela kwiqela le-triptane zisebenza njani?
Indlela esemqoka yomsebenzi walolu hlobo lweziyobisi kukukhuthaza ama-receptors yeendonga ze-vascular. Ukongezelela, i-tryptans ivelise umkhethe kwaye isebenze kuphela phakathi kwexesha elide, ngaphandle kokuchaphazela inkqubo yokujikeleza kwendlela yokuhamba kunye neyomda. Ngenxa yoko, imithwalo yegazi eyancitshulwa ngokugqithiseleyo, egalela ekunciphiseni ngokukhawuleza kwintlungu yesifo sesifo.
Ukongezelela, izidakamizwa ezichazwe zinciphisa ubuzwe beentlanga ezifumana izigulane zentlanzi kwizinga le-nucleus yomgogodla. Ngenxa yobu buhlungu abuzange buve.
Ukongezelela ekulawuleni ngokukhawuleza kweempawu ze- migraine , kubandakanywa isicathulo, ukukhanya kunye nesandi, isizululwazi, imichiza yeli qela isetyenziselwa iinjongo zokukhusela. Ukunciphisa ngokukhawuleza ukuvuvukala kwe-neurogenic nokuthintela ukutshatyalaliswa kwimithambo yegazi.
I-Triptans inezinzuzo ezininzi ngaphezu kwee-analgesics eziqhelekileyo:
- kubangela imiphumo embalwa yecala;
- Musa ukukhupha umlutha kunye nesidingo sokwandisa umlinganiselo;
- basebenze nasiphi na isigaba sokuhlaselwa;
- ukuthintela ukuqhubela intlungu, ukuba uthathe ipilisi kwiimpawu zokuqala;
- ukukhulula iimpawu ze-aura;
- umzabalazo wokubonakaliswa kwezifo zesifo.
Ziziphi iziyobisi ezihambelana nama-triptan?
Amachiza akwiyo mbuzo akhetha ama-5HT18 / D abaphikisanayo. Ziyimveliso yamachiza ye-5-hydroxytryptamine, efunekayo ngamagama.
Kukho izizukulwana ezimbini zezidakamizwa ezinama-triptans. Iyokuqala iquka onke amayeza asekelwe kwi-sumatriptan-ummeli wokuqala kunye nokufundisisa ngokupheleleyo. Isizukulwana sesibini sibandakanya amayeza anamazinga alandelayo:
- zolmitriptan;
- eletriptan;
- naratriptan;
- almotriptan;
- rhizotriptan;
- lt; / RTI & gt;
Amachiza amatsha aneempembelelo ezongezelelweyo zonyango kunye nezinto eziphuculweyo zezilwanyana. Banceda ngokukhawuleza kwaye bangela iziphumo ezincinci.
Kubalulekile ukuba uqaphele ukuba i-almo-, i-rhizo- kunye ne-fluorotriptans ziqhubeka zivavanywa kwaye ziqhuba uphando, ngoko zisafumaneki mahhala.
Uluhlu lwezilwanyana ezisuka kwimigraine ukusuka kwiqela lama-triptans
Ukuzithatha amayeza kwintsholongwane kungcono phantsi kokubhaliswa kogqirha. Nangona kukho indlela efanayo yezenzo ze-triptans, isigulane ngasinye sincedwa lunye uhlobo lwamayeza, oluya kunceda ukhethe uchwepheshe emva kokufunda ngokucophelela impawu nganye yesigulane kunye ne-anamnesis.
Uluhlu lweziyobisi:
1. I-Sumatriptans:
- Ukukhawuleza;
- Imigran;
- Sumatriptan;
- Trimigrene;
- Amigrenin;
- Sumygamren.
2. iZolmitriptans:
- Zomig.
3. ii-Eletriptans:
- Relpaks.
4. Naratriptans:
- Naramig.
Phantse isiqingatha sabantu abahlaselwa yi-migraine zihlaselwa intloko ephakathi kweentsuku ezingama-2 kunye namayeza achazwe. Ngoko ke, ubuncinane ubuncinane iiyure ezingama-2 emva kokuthatha i-tryptane, kucetyiswa ukuba uthathe elinye ipilisi yesilwanyana. Kubalulekile ukuba ungadluli i-dosage ephakanyisiweyo.