I-hormone ye-Glucocorticosteroid iyimfuneko ebalulekileyo kwimimiselo yonyango ekwenzeni izifo ezininzi ezihamba neenkqubo zokuvuvukala. Kubandakanya i-Dexamethasone - injections yale nkunkuma isebenza kakuhle kwaye ngexesha elifanayo likhuselekile. Xa kuthelekiswa nezinye i-glucocorticosteroids, eli arhente lenza iziphumo ezincinci.
Iimpawu ze-Pharmacological zeejoke zonyango uDexamethasone
I-ejenti ejongene ne-hormonal ivelisa ezintathu iziphumo eziphambili emzimbeni:
- ezichasayo;
- immunosuppressive;
- antiallergic.
Ukongezelela, isisombululo seDexamethasone sinciphisa i-edema yeembrane ezinqabileyo zendlela yokuphefumula, okuyimfuneko ekwenzeni unyango lwe-bronchi, kunye nokunciphisa i-viscosity yemfihlelo eyimfihlo, iququzelele i-excretion ngexesha lokukhwehlela.
Ziziphi iilject zeDexamethasone?
Okokuqala, isilwanyana esisetyenzisiweyo sisetyenziswa kwi-hormone yonyango yokuguqula izifo ze-endocrine:
- i-hypoplasia yokuzalwa yesibalo se-adrenal cortex;
- Isifo sika-Addison;
- Ukungaphumeleli ngokukodwa kwe-correnx ye-adrenal, zombini eziprayimari nezesekondari;
- i-acety and subacute thyroiditis;
- i-adrenogenital syndrome;
- i-tumper hypercalcemia;
- hypothyroidism.
Iimpawu ezisele zokusetyenziswa kwee-Dexamethasone:
Umqathango otshitshisayo:
- emva kokusebenza;
- emva kokubuhlungu;
- ukumpontshelwa igazi;
- i-cardiogenic;
- kutshisa;
- inetyhefu.
2. I-pathology yenkqubo yokuphefumula:
- isimo se-asthmatic;
- i-infhma-infermaal-inflammatory infhma;
- sarcoidosis ;
- ukukhushulwa kwe-bronchitis engapheliyo;
- bronchospasm enkulu;
- Isifo seLeffler;
- sasazwa ngesifo sofuba;
- brilliosis.
3. I-edema yeCerebral nge:
- i-craniocebral trauma;
- ukurhoxisa;
- iimvumba;
- encephalitis;
- imisebenzi ye-neurosurgical;
- ukulimala kwemisebe yemiphunga;
- i-meningitis.
4. Izifo zeRheumatic:
- isifo senhliziyo esisisigxina;
- i-rheumatoid arthritis ngexesha lokuxhatshazwa;
- sasazwa i-lupus erythematosus.
5. Inemia:
- idiopathic;
- ngokuzenzekelayo;
- kuzalwa;
- erythroblastopenia;
- hemolytic;
- hypoplastic.
6. Izifo zesistim sokutya:
- i hepatitis;
- nephrotic syndrome;
- i-ulcerative colitis.
7. Iinkqubo ezinokukhuphaza kunye nokuvuvukala kwiindawo kunye nezihlunu:
- tenosynovitis;
- epicondylitis;
- arthritis;
- bursitis;
- osteochondrosis;
- styloidite;
- Isifo sikaBechterew;
- osteoarthritis;
- myositis.
8. Izifo zegazi:
- thrombocytopenia yesibini;
- lymphomas;
- i-lymphocytic leukemia;
- idiopathic thrombocytopenic purpura;
- leukemia;
- plasmacytoma;
- agranulocytosis.
9. I-pathologies ye-Ophthalmic:
- keratitis;
- irit;
- i-conjunctivitis;
- blepharitis;
- iridocyclitis ;
- keratoconjunctivitis;
- sclerite;
- ophthalmia;
- blepharoconjunctivitis;
- episcleritis;
- ukuvuvukala emva kokusebenza kwamehlo.
10. Uluhlu lwesikhumba:
- i-redus lupus erythematosus;
- keloids;
- granuloma yonyaka;
- ezinzima kakhulu zedermatosis.
Ii-injini zeDexamethasone nazo ziyalelwe ukuba zithinteke, izilonda zesistim zezifo ezixhamlayo kunye nezifo ezinzulu. Kwimeko yokugqibela, izidakamizwa ze-hormonal zidibeneyo kunye ne-antibiotic.
Ungayifaka njani i-Dexamethasone ngokufanelekileyo?
Ngeemeko eziphuthumayo kwaye ezinzima, ii-injection zangaphakathi zonyango zinikezelwa kumyinge we-4-20 mg (kuxhomekeke kwi-pathology ebonakalayo) ukuya kumaxesha amane ngosuku. Ijoza kufuneka yenziwe ngokukhawuleza, ubuncinane ubuncinane ngomzuzu.
Ukuba isimo sempilo sinelisekile, isilwanyana kufuneka silawulwe nge-intramuscularly kwiqondo elifanayo.
Inkqubo yonyango olunjalo yiintsuku eziyi-3-4, ukugcina i-dose emva kokunciphisa ukukhushulwa - 0.2-9 mg ngeeyure ezingama-24. Ukuba kukho unyango olongezelelweyo, iya kuDexamethasone ngendlela yamacwecwe.
Maxa wambi ama-injection ene-intra-articular kunye ne-interstitial injections. Kwiimeko ezinjalo, i-dose yemihla ngemihla yesirmoni i-0.2-6 mg.
Ukutshatyalaliswa kunye nemiphumo emibi yeejoke zeDexamethasone
Izifo kunye neemeko apho isisombululo esichaziweyo asinakusetyenziswa:
- i glaucoma;
- izilonda ezithintekayo zezicubu kunye namajoyina;
- hypersensitivity;
- i-amoebic;
- uhlobo olusebenzayo lwesifo sofuba;
- i-mycosis;
- izifo ezikhuselekileyo zonyango;
- ixesha ngaphambi nangemva kokugonywa.
Ngokumalunga nemiphumo emibi, iDexamethasone, njengomthetho, iyakunyamezela. Kwiimeko ezinqabileyo, zikhona iingxaki ezingekho nengozi ezivela kwiindlela ezilandelayo zomzimba:
- yokutya;
- i-cardiovascular;
- endocrine;
- utyhafile;
- musculoskeletal;
- omzimba.
Ngamanye amaxesha izimpembelelo zesikhumba nezendawo zenziwa, i-calcium metabolism, ukuqonda ezinye izitho zengqondo ziphazamiseka.