I-Cirrhosis isifo esihamba kunye nokutshintshwa kweeseli ezinobungozi ezinobungozi (hepatocytes) kunye nezicubu ezinobumba ezingakwazi ukwenza imisebenzi yazo. Ifomu eqhelekileyo yesi sifo i-cirrhosis ye-biliary, ibonakaliswe ngeendlela ezimbini - eziprayimari nezesekondari. Zizobonakalisa iimpawu ezifanayo, kodwa izizathu ezihlukeneyo zenzeke.
I-cirrhosis yebhiliyari yeprayimari yesibindi
Isifo sisimo semvelo kwaye siqala ngokuvuvukala okungapheliyo kwiphepha le-biliary (cholangitis), ngenxa yeyiphi i-cholestasis eqhubeka ngaphezu kwexesha, oko kukuthi, i-bile ngokupheleleyo okanye iyancipha ukungena kwi-duodenum. Le ngxaki ekugqibeleni ikhokelela kwi-cirrhosis eyimphambili ye-biliary, iimpawu zazo zilandelayo:
- ukukhumba isikhumba, ngakumbi ukukhathazeka ebusuku, okuyiminyaka emininzi;
- ubuthathaka obuthathaka;
- intlungu kwi-hypochondrium efanelekileyo;
- ukubumnyama kwesikhumba emagxeni, ukuxhamla kwamalungu, kunye nokuphuhliswa kwesi sifo, ulusu luba mnyama emzimbeni wonke;
- ipeni ekhulisiweyo;
- intlungu;
- inambitheka emlonyeni;
- ngxamele ukutya;
- lokushisa komzimba.
Izigulane ezininzi kude kube nezigaba zokugqibela zesi sifo. Ukubamba isikhumba kungaba sisizathu sokutyelela kwidermatologist.
Ekupheleni kweesigaba ze-cirrhosis, i-hydrocephalus ( ascites ) ikhula.
Phakathi kwezigulana ezine-cirrhosis zesibindi, ubuninzi abafazi bafunyanwa, kodwa amadoda ahlupheke kaninzi.
Ekuphuhlisweni kwesilonda seeseli zesibindi indima ebalulekileyo idlalwe yizinto eziza kuzalwa.
I-cirrhosis yebhilidi yesibini
Le fomu ivela ngenxa yokhuselo olude (umqobo) we-buct ye-bony ebizwa ngokuba yi-cholechae. Izizathu zengxaki zibandakanya i-cholelithiasis kunye nemisebenzi ephathelene nokuhlinzwa, kunye ne-pancreatitis engapheliyo kunye neoplasms.
I-symptomatology ye-cirrhosis yesibini ye-biliary ilandelayo:
- ukubetha;
- ukuphuka kwe-sclera kunye nolusu (lukhula ngokukhawuleza kwaye lukhulu);
- utshintshe ngombala weemfesi (ukuguqulwa kwazo);
- utshintshe umbala we-urine ukuya kumnyama omnyama;
- intlungu kwi-hypochondrium efanelekileyo;
- ukwandiswa kweseyile .
Ngokuqhelekileyo, le miqondiso incediswa yi-cholangitis eneengxaki ezithintekayo, ezihamba kunye nokunyuka kweqondo lokushisa komzimba ukuze kufumaneke amanani, ukukhupha, ukujuluka.
Kwinqanaba lexesha elizayo, oko kuthiwa. i-portal hypertension, eyinyukiselo kwingcinezelo kwi-veal vein, kunye nesinye isibonakaliso sesimo se-cirrhosis-ukungenakusebenza kwe-cell.
I-cirrhosis yesibini yebhilidi yesibindi ihlala ichaphazela abantu abaneminyaka engama-30 ukuya ku-50 ubudala.