IHymmone yokukhula

I-hormone yokukhula (STH), njengoko ibizwa nangokuthi, i-hormone yokukhula, yintlobo yeprotheni yemvelo eyenziwe kwintsimbi ye-pituitary yangaphambili. Umsebenzi oyintloko owenziwe nguye kukukhuthaza ukukhula, kwaye ngenxa yoko-ukwanda kwomeko lomzimba. Oku kufezekiswa ngokusetyenziswa kweenkqubo ze-anabolic. Ukongeza, le hormone ikwandisa umsebenzi weoli, i-carbohydrate, kunye ne-metabolism yamaminerali.

Yintoni eyenza ukuhlanganiswa kwe-hormone yokukhula emzimbeni?

Bobabini inqubo ye-biosynthesis kunye nesigcino esilandelayo se-hormone yokukhula kuxhomekeke kwimpembelelo eyahlukeneyo yokuba inkqubo ye-nervous, ingakumbi kwiingqungquthela zangasese zangaphakathi, inomzimba. Yona inkqubo yokuqulunqa ilawulwa yi-hypothalamus, ngokuchanekileyo ngeeurohormones zayo.

Impembelelo ye-STH emzimbeni yenziwa yi-insulin-efana, iimeko zokukhula, kwaye kuxhomekeke kwimbini kunye nomsebenzi wee-tissue receptors ze-hormone.

Kwenzeka njani ukuhla kwe-STH emzimbeni?

I-hormone yokukhula ngokuqhelekileyo iyancipha ebuntwaneni. Ukuba le nyaniso ayitholakali ngexesha kwaye ayilungiswanga, sele ikhulile, ukukhula kwabantu abanjalo akudluli kuma-130-140 cm. Ngelo xesha, ukwehla okuhambelana nobukhulu bezitho zangaphakathi kugcinwa, eyaziwa kwiyeza njenge splanchnomycria. Kwizi gulane, i-hormonal kunye neengxaki ze-metabolic nazo ziyabonwa. Ngokuqhelekileyo ukutshatyalaliswa kwentsholongwane kukhula.

Yintoni eyenzekayo kumzimba ngokugqithiseleyo kwe-STH?

I-hormone yokukhula inokunyuswa emzimbeni phambi kwesohlwayo sokunyuka kwama-hormonal nature. Ngelo xesha, ngokuxhomekeke kwinqanaba apho i-disorder ivela khona, ezimbini iikliniki ze-syndromes ziyahluka:

1. Kwabantwana, ababenokuqulunqwa kwe-ossification, ukunyuka kwethambo kubangele ukukhula okuphezulu, okubangele ukuphuhliswa kwe-gigantism.
2. Ukuba ukukhubazeka kwenzeka kubantu abadala abaye baqukunjelwa inkqubo yokugqithisa, kukho ukunyuka kokukhula kwethambo kubanzi, ekugqibeleni kukhokelela ekunyuseni kwimizimba yezicubu zomzimba. Ngenxa yoko, kukho ukunweba kwamathambo emasipha, kunye nokuyeka, ukuguqulwa kwamalungu, ukwanda kwipumphu kunye neendlebe. Wena, ngamanye amazwi, i-acromegaly iyaqhubeka.

Ukwandiswa kwamanqanaba e-blood glucose egazini kunokubangelwa nokuthatha imishishini, ngokukodwa, equkethe i-glucocorticoids kunye neprogesterone.

Yiyiphi inqanaba le-STH emzimbeni kufuneka liqheleke?

Izinga lokukhula kwehommone egazini litshintsha ngobudala. Ngexesha elifanayo, ukuxilongwa kwangaphambili kunye nokunyangwa kwexesha elifanelekileyo, kubaluleke kakhulu ukulawula izinga lokukhula kwehomoni kubantwana. Ishintsho salo shintsho ngolu hlobo:

• abantwana 1-3 iminyaka: abafana (m) - 0.43-2.4 ng / ml; amantombazana (e) - 0.5-3.5;
• 4-6 iminyaka: m - 0,09-2,5; d - 0,1-2,2;
• 7-8 iminyaka: m - 0,15-3,2ng / ml; d - 0.16-5.4;
• Iminyaka eyi-9-10: m - 0.09-1.95 ng / ml; i-0,08-3,1.

Ukuba ukrokrela ukukhubazeka kwabantwana, uhlalutyo lwenziwe ngezinga lokukhula kwehomoni, iziphumo zazo ezifaniswa nesiqhelo. Kule meko, kwindawo yokuqala uqwalasele iminyaka yobudala bomntwana.

Njengabantu abadala, isiqhelo sale hormone egazini lifikelela kwi-1.0 ng / ml. Nangona kunjalo, ukuphakama kwintsholongwane, umzekelo, kwi-acromegaly, kufinyelela kwi-40-80 ng / ml. Ukwanda kwe-hormone kule nqanaba kuyafana noku:

• gigantism;
• I-CRF (ukungaphumeleli kwe-renal );
• ngxakini ;
• izidumbu kwimiphunga, esiswini.

Ngaloo ndlela, ngokukhula komntwana ukusa ngasemva, kubaluleke kakhulu ukuxilongwa kwexesha lokuhlaselwa kwe-pathology, kukukhula kwe-hormone test.