I-Rarr-A ekukhulelweni - isiqhelo

Iingcamango malunga nokuqhelwaniswa kweziboniso zangaphambi kokubeletha ziyahlukana. Abanye bakholelwa ukuba esinye isizathu sokukhathazeka. Abanye baciniseka ukuba uhlalutyo lunokuba ngumqondiso wokuqala malunga nosongelo lwangempela. Nangona kunjalo, kungcono ukukhuseleka, ngakumbi kule micimbi ejongene nempilo yengane ezayo. Ngokukodwa, uhlalutyo lwe-Rarr-A ukukhulelwa (uguqulelo lwe-Russian-Papp-A), oluqhutywa ngethuba lokuqala lokuhlola , luya kunceda ukucacisa umfanekiso.

Uhlalutyo lwe-Rarr-A (Papp-A) ekukhulelweni - yintoni intsingiselo?

Ummakishi obonisa umngcipheko wokuzala abantwana kunye neengxaki kwizinga lomlibo lizinga le-Rarr-A ekukhulelweni, okanye ngokuchanekileyo - ukuthotyelwa kwayo. Ukuba uyichaza ngokwenene kwaye uguqulela ukusuka kwisiNgesi lesi sishwankathelo, ngoko-Rarr-A ayikho into ephakanyisiweyo yiprothini ene-A-plasma ehambelana nokukhulelwa.

Oogqirha bancomela ukuba bahlolisiswe kwiiveki ezi-8 ukuya kwezi-14 zokukhulelwa. Kodwa, ekubeni i-RARR-A imiselwe ngokubambisana neHCG, ixesha elifanelekileyo lokuthatha uvavanyo lwe-RARR-A lokukhulelwa lixesha eliphakathi kwe-11 ukuya kweleveki ezingama-13. Kule nqanaba, iziphumo ziya kuba njengolwazi njengoko kunokwenzeka.

Ngenxa yokuba i-Rapp-A ingabonisa i-chromosomal engafanelekanga yefubus, uvavanyo oluphindwe kabini lukhuthazwa ukuba lugqithise kubafazi:

• ngaphezu kweminyaka engama-35;
• sele sele unabantwana abaneengxaki ezifanayo;
• neentsapho ezineengxaki zokuzalwa;
• Kungekudala ngaphambi kokukhulelwa, i-rubella, i-hepatitis, i-herpes okanye i- cytomegalovirus ;
• kunye nokukhulelwa okunzima okanye okuphazamisekile ngexesha lokuqala, ngexesha elidlulileyo.

Ukuba i-Rarr-A ngexesha lokukhulelwa ayihlangabezani nesigqirha, ugqirha uya kunika uviwo olongezelelweyo ukuze kuqinisekiswe ukuba konke kulungile nomntwana.

Iyunithi yesilinganiselo i-RARR-A-mU / mL, kwaye imida yesiqhelo ixhomekeke kwiminyaka yobudala, ngoko:

• 0,17-1,54 uluhlu lweemilinganiselo ezivumelekileyo kwixesha leeveki eziyi-8-9;
• 0.32-2.2-9.10;
• 0.46-3.73-10.11;
• 0.79-4.76-11.12;
• 1.03-6.01 - 12-13.

Ukunciphisa nokuphakanyiswa kwe-RARP-A (Papp-A) ekukhulelweni

Ukuba uhlalutyo kwi-Rarr-A (Papp-A) ngexesha lokukhulelwa lunomxholo ophantsi kweli protein kumzimba kamama, oku kungabonisa ukuba kunokwenzeka ukuba ube ne-chromosomal engafanelekanga. Kwakhona, ixabiso elingaphantsi lingabonisa isongelo sokukhulelwa kwesisu okanye ukukhulelwa okukhukhulayo.

Ukuba i-Rahr-A ngethuba lokukhulelwa liphakanyisiwe, ngoko kwenzeka ukuba kukho impazamo ekuqaliseni ixesha lokukhulelwa. Ngoko ke, iingcali zincoma, ngaphambi kokwenza uvavanyo, kuqala ukuba ziqhube i-ultrasound, ukwenzela ukuba zichongwe ixesha elichanekileyo lokubamba. Ngexesha elifanayo, ixabiso elinyusayo alithinteli ithuba lokungahambi kakuhle kwempilo.