Ixesha lokulungiselela ukukhulelwa okuzayo kumama ozayo lidibene nezifundo ezininzi. Phakathi kwabo, kunye nohlalutyo lwalo hlobo njenge-homocysteine. Cinga le ngcaciso ngokubanzi, siya kufumanisa: kutheni i-homocysteine ichongiwe ekucwangciseni ukukhulelwa, zeziphi izibonakaliso zendalo kunye nento ekhokelela ekunyuseni nasekunciphiseni.
I-Homocysteine - yintoni na kubasetyhini?
Xa uthumela umfazi kuhlalutyo, owenza iqondo le-homocysteine egazini, luhlobo luni lophando oluninzi lwabafazi abangasazi. Le nkunkuma yinto yokuvelisa i-methionine (i-amino acid). Umgangatho we-homocysteine egazini ngokunyuka ukhula kunye nobudala, nangona kunjalo, xa ukhulelwe, ukunyanzeliswa kwalo kunciphisa (i-1st and 3rd trimesters).
I-Homocysteine ekucwangciseni ukukhulelwa kubalulekile ukujonga ngenxa yefuthe layo elibi kwinkqubo yokubamba. Ngeli xesha, le nkunkuma inefuthe ngqo kwi-circulation circulation, apho uphuhliso olufanelekileyo lwe-intrauterine lomntwana kunye nejubane layo lusekeke. Oogqirha bayakubona kuyimfuneko ukuseka ukuxinwa kwe-homocysteine kwinqanaba lokulungiselela ukukhulelwa okuzayo ukuze uphendule ngexesha lokunciphisa okanye ukunyuka, kwaye uthathe amanyathelo.
Yintoni i-homocysteine ibonisa?
Ukufunda ukuba yintoni i-homocysteine, i-mother-in-mother in the stage of preparation for pregnancy ubuze oogqirha umbuzo - yintoni uhlalutyo olwenziweyo, kwaye lubonisa ntoni. Ngokusekelwe kwiziphumo, oogqirha bafumana izigqibo malunga neenkqubo ze-intracellular kumzimba womfazi. Ngoko ke, ukuba i-metabolism ye-homocysteine iphazamisekile, iqokelela kwisikhundla se-extracellular, kwaye kwi-plasma yegazi. Kwiindawo eziphezulu, i-compound inefuthe le-cytotoxic.
Ngenxa yolu hlobo lwenkqubo, kunokubakho ukuphulwa kwentembelelo yeendonga zeempahla - ubuso babo buya kukhululeka. Kwiindawo zonakaliswe, i-calcium kunye ne-cholesterol zihlala kwindawo yamanzi. Ngenxa yolu tshintsho, ukusekwa kweplathi ye- atherosclerotic kwenzeka. Oku kwandisa umngcipheko weengcambu zegazi kwimithanjeni yegazi, echaphazelekayo nokuphuhliswa kwe-thrombosis ngexesha lokukhulelwa.
Kutheni uthatha i-homocysteine ngelixa uceba ukukhulelwa?
Umgangatho we-homocysteine egazini uvumela oogqirha ukuba bafumane izigqibo malunga neenkqubo ze-intracellular. Ukuphambiswa kwe-metabolism kwandisa umngcipheko wegazi kwiimithana zegazi. Olu tshintsho lugqityiwe nokuvalwa kweemvini ezise-placenta. Ngenxa yoko, kukho ukuphulwa kwe-intrauterine yophuhliso lomntwana ngexesha lokukhulelwa. Ukukuthintela, oogqirha bazama ukuchonga i-pathology kunye nokuxhomekeka kwayo kwisigaba sokucwangcisa.
Uhlalutyo lwe-Homocysteine lokucwangcisa ukukhulelwa
Ukuchonga izinga le-homocysteine ekucwangciseni ukukhulelwa, oogqirha bajonga abafazi kuhlalutyo. Kule meko, oogqirha bancomela ukuba bangene kule ngcaciso 3 inyanga ngaphambi kokuqala kocwangciso. Ukuba ngaba umama wesikhathi esizayo wayenengxaki ngeengxaki zemethambo emzimbeni we-homocysteine, isifundo senziwa ngaphaya kweenyanga ezintandathu ngaphambi komhla wokulindela kokuzalwa.
Homocysteine - ukulungiselela
Ukuze uhlalutye i-homocysteine ngexesha lokucwangcisa, kuyafuneka ukuba ugcine imigaqo emiselweyo kwisigaba sokulungiselela. Ukwenza oku:
- Ngenye imini ngaphambi kwexesha lokumisela igazi, kuyimfuneko ukukhuphela ukutya okunesonka kunye notywala ekudleni.
- Ngomhla ngaphambi kokufundisisa, imisebenzi emzimbeni enzulu ayinqatshelwe.
- Iiyure eziyi-8-14 phambi kokusampula isampuli yegazi akuvunyelwe ukuthatha ukutya, kuphela ukusela (okulula, namanzi) kuvunyelwe.
- Musa ukutshaya imizuzu engama-30 phambi kovavanyo.
Homocysteine - njani ukuthatha?
Ngaphambi kokuba uthathe i-homocysteine ngelixa uceba ukukhulelwa, umfazi ufumana ukuthunyelwa kogqirha. Isifundo ngokwayo senziwa kusasa ngesisu esingenalutho. Uhlalutyo lwenziwe ngokuthatha isampuli yegazi kwi-vein vein. Ukuchonga i-homocysteine ekucwangciseni ukukhulelwa kwangaphambili, 2-5 ml yegazi ithathwa, ebeka kwi-tube oyinyumba, ibhalwe kwaye ithunyelwe kwi-laboratory. Iziphumo zingatholakala kwiintsuku ezingama-2-3, kuxhomekeke kumthwalo womsebenzi weziko lempilo.
I-Homocysteine - isiqhelo kubafazi xa behlela ukukhulelwa
Umlinganiselo we-homocysteine xa uceba ukukhulelwa ngu-10-11 μmol / l. Le ngxubusho ithathwa njengesiqhelo somzimba. Ukuphambuka kubonisa ukuphulwa, kwaye kufuna ukuba kusetyenziswe amanyathelo okulungisa. I-algorithm yokuphunyezwa kwayo iphuhliswe ngokwayo, ingqalelo imeko kawonkewonke yomzimba wesetyhini, ubukho bezifo ezingapheliyo kunye neenkqubo zokugula. Ukuthotyelwa kweziphakamiso zezokwelapha ezifunyenweyo kunye nemigqaliselo, kunceda ukuphelisa ngokukhawuleza ukuphulwa, i-homocysteine echanekileyo, okuqhelekileyo kuboniswe ngasentla.
I-homocysteine ephezulu ekucwangciseni ukukhulelwa
Ngokuqhelekileyo ukuxinwa kwe-homocysteine kubangelwa ukungaqhelekanga kokukhulelwa. Ngenxa yoko, ukulungiswa kufuneka kwenziwe kwinqanaba lokucwangcisa. Ngaphambi kokuba u-homocysteine unciphise, oogqirha baqhuba uviwo olunzulu olujoliswe ekumiseni imbangela yokwanda. Inkqubo yendlela yokunciphisa i-homocysteine iphuhliswa ngokuqwalasela isifo se-pathological factor:
- Ukunciphisa izinga lamavithamini e-B. Kule meko, oogqirha babonelela ukutya kunye nomxholo ophezulu we-thiamine, i-pyridoxine, i-folic acid.
- Impembelelo ye-nicotine. Kwafunyaniswa ukuba ukutshaya kubangela ukwanda kwinqanaba le-homocysteine. Ukunciphisa kufuneka ulahle i-nicotine .
- Caffeine. Xa usela ikofi, ukuxinwa kwe-homocysteine kwanda. Ukuze uyanciphise, kufuneka ukhuphe ngaphandle kokusela.
- Izinga eliphantsi lomsebenzi. Ukusebenza okusebenzayo kunceda ukunciphisa i-homocysteine.
I-Homocysteine iyancipha xa ihlela ukukhulelwa
Ukuqonda indlela yokunciphisa i-homocysteine ekucwangciseni ukukhulelwa, kufuneka kuthathelwe ukuba imeko echasene nayo ibonakalayo-ukungabikho kwayo. Ukuba i-homocysteine iyancipha kancane, oku akunakuchukumisa nayiphi na indlela inqubo yokuzala umntwana. Ukuxhalabisa kulungele ukubethelwa xa i-homocysteine ephantsi kakhulu imiselwe - 4.1 μmol / l kwaye iphantsi. Kwiimeko ezinjalo, oogqirha banika unyango okhethekileyo ukwandisa izinga lezinto. Umama onokuza naye unokuthatha amanyathelo okulungisa izinga le-homocysteine:
- Ukunciphisa umsebenzi omzimba okhuselekileyo - ukukhuphela ngaphandle kwexesha loqeqesho lwezemidlalo.
- Ukusela ikhofi ekuseni.