I-Aminoglycosides iquka iqela le-antibiotics elibonakaliswe kwisakhiwo esifanayo, umgaqo wesenzo kunye neqondo eliphezulu lokutywala. Amalungiselelo ase-Aminoglycoside anesakhiwo esicacileyo se-antimicrobial kwaye asebenza ngokubhekiselele kwi-Gram-positive ne-Gram-negative bacteria.
Ukwahlulelwa kwe-aminoglycosides
Ngokuxhomekeke kwintsimi yesicelo kunye nexesha lokuphuhliswa koxhatshazo, izizukulwana ezine zamachiza zabiwe. Makhe siqwalasele iimpawu ezisisiseko kwaye siya kubangela uluhlu lwamagama amalungiselelo-aminoglycosides.
Amachiza okuQala
Ezi zi:
- Neomycin;
- Streptocin;
- Monomycin;
- Kanazin.
Zisetyenziselwa unyango malunga nezifo zesifo sofuba kunye nezinye iibhaktheriya. Ukulwa ne-staphylococci kunye ne-gram-negative bacteria, iziyobisi azizinamandla. Ngoku ngoku asebenzisekanga.
Aminoglycosides yesizukulwana sesibini
Ummeli weqela lesibini le-antibiotics-aminoglycosides yi-Gentamicin, esebenza kakhulu kuneqela elidlulileyo leziyobisi.
Isizukulwana sesithathu se-aminoglycosides
I-spectrum yeempembelelo zesizukulwana sesithathu iyafana ne-Gentamycin, nangona isebenza ngokuthe ngqo kwi-enterobacter, klebiciella kunye ne- Pseudomonas aeruginosa . Eli qela liquka:
- Sisomycin;
- Tobramycin;
- Amicacin.
Isizukulwana sesine
Eli qela liquka i-antibiotics i-Izepamycin, eyongezwayo yokulwa ne-nocardia, i-cytobacter, i-aeromonas.
Imiphumo emibi ye-aminoglycosides
Ngethuba lokunyanga ngala mayeza, isigulane sinokuhlangabezana nenani lezinto ezingafunekiyo. Impendulo eyintloko yeziyobisi inetyhefu. Ibonakala kubonakaliso obulandelayo:
- I-Ototoxicity, ekhokelela ekuhlahleni kwenyameko yokuva, ukubonakala kwengxolo ezindlebeni, ukuvakalelwa.
- Impembelelo yeNefrotoxic, iimpawu zazo zome, zitshintshe kwisixa somchamo, ukunciphisa ukuhlanjululwa kwe-glomerular.
- Ukudityaniswa kokuhambelana nokuhamba kunye nokuzondla, okuyiyona nto ibalulekileyo ngabantu abadala.
- Ngenxalenye yesimiso seentlanzi, ukuphazamiseka emlonyeni, ukuphazamiseka, ukuthathaka, intloko, ukutshatyalaliswa kwintlungu, ukulala.
- Ukubonakala kweempawu ze-neuromuscular blockade, kubonakaliswe ekudlukisweni kwemisebenzi yokuphefumula ukuya kwi-paralysis ejongene nokuphefumula, ukunyusa umngcipheko ngokulawulwa ngokufanayo kweziza-antibiotics-i-aminoglycosides kunye ne- relaxation muscle kunye ne-anesthetics, kunye nokuxutywa kwegazi elixubileyo.
Izibonakaliso zempembelelo ezithintekayo ziyabunqabile.