Umntwana wakho wagula, kwaye ugqirha wamisela ukuhlolwa kwegazi jikelele. Ngokweziphumo zakhe, kwavela ukuba igazi lomntwana landa izinga le-alkaline phosphatase. Abazali, ngokuqinisekileyo, bazibuze ngokukhawuleza ukuba yiyiphi i-alkaline phosphatase enoxanduva kwaye yintoni na isalathisi nonke.
Yintoni i-alkaline phosphatase ibonisa?
I-alkaline phosphatase yiqela leenzyme eziqulethwe kuzo zonke izicubu zomzimba womntu. Ininzi i-alkaline phosphatase ifumaneka kwiithambo zethambo, i-osteoblasts, i-bile ducts. Umthamo ophezulu uyabalwa yi-mucosa yamathumbu. I-alkaline phosphatase ikhiqizwa ngumgca womhlaba we-mucosa wamathumbu, kodwa ithatha inxaxheba kwiinkqubo zokugaya isibini. Umsebenzi oyintloko we-alkaline phosphatase yi-acafe ye-phosphoric acid, efunekayo emzimbeni, kwiimveliso ezihlukahlukeneyo ze-organic. Le enzyme iququzelela nokuthuthwa kwe-phosphorus kuwo wonke umzimba.
Umxholo olandelayo we-alkaline phosphatase kubantwana uthathwa njengesiqhelo:
- ekuzalweni -
- ngomhla wesihlanu emva kokuzalwa -
- ukususela kwiintsuku ezingama-6 ukuya kwiinyanga ezintandathu -
- ukususela kwiinyanga ezi-6 ukuya kunyaka-1
- ukususela kunyaka omnye ukuya kwiminyaka emithathu -
- ukususela kwiminyaka emi-4 ukuya kwiminyaka engama-6
- ukususela kwiminyaka eli-7 ukuya kwiminyaka eyi-12 -
- ukususela kwiminyaka eyi-13 ukuya kwiminyaka eyi-17 (amakhwenkwe)
- ukususela kwiminyaka eyi-13 ukuya kwiminyaka eyi-17 (amantombazana) -
Iirhafu ze-enzyme kwi-serum yegazi ziyakwazi ukuhluka ngokuxhomekeke kwiindlela zophando kunye nezixhobo ezisetyenziswayo.
Ekusebenzeni kwezilwanyana, uvavanyo lwe-alkaline phosphatase ludlala indima ebalulekileyo ekuxilongweni kwesifo sesibindi, ehamba kunye nokuhla kwe-bile ehamba kwi-duodenum. Kule meko, i-alkaline phosphatase egazini lomntwana idla ngokunyuka. Inqanaba eliphezulu le-phosphatase lwenzeka xa kukho ukuphulwa kwe-bile ye-bile ngenxa yamatye kwi-buct buct okanye kwi-tumor ye-bile. Ukongezelela, kunye ne-alkaline phosphatase ephakamileyo kumntwana, ugqirha unokukwazi ukubeka ezi zifo:
- izifo zethambo, kubandakanywa nezicubu, i-sarcoma, i-metastases yomhlaza kwisithambo;
- hyperparathyroidism;
- ukunqotshwa kwamathambo nge-lymphogranulomatosis;
- iiplanga;
- Isifo sePaget (isifo sesifo);
- mononucleosis;
- myeloma;
- i cytomegaly yabantwana;
- izifo zamathumbu.
Kubaluleke kakhulu kubonakaliso be-alkaline phosphatase kubantwana ekuxilongweni kwexesha lokuqala. Kule meko, umsebenzi we-enzyme unyuka ixesha elide ngaphambi kokuba iimpawu zeklinikhi zivele.
Ngamanye amaxesha kukho umzimba, okwangokwemvelo, ukwanda kwinqanaba le-alkaline phosphatase kwi-serum yegazi: kwiintsana ezisenakusana okanye kwiintsholongwane ngexesha lokukhulelwa kunye nokukhula ngamandla kweethambo zenyama.
Xa usebenzisa iziyobisi ezineempembelelo zecala le-hepatotoxic, izinga le-enzyme alkaline phosphatase kumntwana linokuphakanyiswa. Ezi zi yobisi ziquka i-paracetamol, i-penicillin, i-sulfonamides, i-erythromycin kunye nabanye abaninzi. Ngokunyuka kwe-metabolism kwiithambo zethambo ngexesha lokutyunjwa kwamathambo, i-enzyme iphinda iphakanyiswe.
Ukunciphisa izinga le-enzyme alkaline phosphatase ayikho into ebalulekileyo yekliniki. Ukunciphisa kwinqanaba le-enzyme lingaba kunye nokuphulwa kweentlobo ezahlukeneyo zokukhula kwethambo, ukungabikho kokutya kwi-zinc, i-magnesium, iivithamini C kunye ne-B12, ne-anemia kunye ne-hypothyroidism,
Indlela yokunciphisa i-alkaline phosphatase?
Ukuze isalathisi sezinga le-alkaline phosphatase kumntwana ukuba abuyele kwisiqhelo, kuyimfuneko ukunyanga isifo esisisigxina, kwaye kungekhona nje ukulungelelanisa eli nqanaba kumgangatho oqhelekileyo.
Kubantwana, umsebenzi we-alkaline phosphatase uhlala uphezulu kunabantu abadala. Kwezinye iimeko, ukwanda komsebenzi we-phosphatase kukuphela kwesifo sesifo esinesifo esibi. Ngako oko, kubaluleke kakhulu ukwenza zonke izifundo ezifunekayo zekliniki kwaye uqale unyango lomntwana wakho ngexesha, eliya kubakho ukuphucula ngokukhawuleza.