I-Saitotec yokukhipha isisu

I-Saitotec - yesibini kwi "tandem" iziyobisi ezisetyenziselwa ukukhipha isisu. Iyokuqala kweziyobisi nguMifepristone.

I-Saitotec, njengabalingani bayo (Misoprostol, Mirolut, Cytotec, iMisonyuvel) kukulungiswa kwe-misoprostol kwaye ifumaneka njengamacwecwe, nganye iqukethe i-200 μg yesithako esisebenzayo.

Izibonakaliso zokusetyenziswa kwesi siza zinomdla kakhulu. Isilwanyana singasetyenziswa zombini ukunyanga kwesilonda sesisu kunye nenjongo yokukhipha isisu . Ezinye iinkampani zonyango-abavelisi i-Saytoteka kwimigaqo yokusetyenziswa kwisikhundla seziyobisi nje kuphela njenge-antiulcer. Abanye abavelisi kwiluhlu lweenkcukacha zibonisa ukuba kungenzeka ukusebenzisa ii-tablet ze-Saitoteka ukuphazamisa ukukhulelwa.

I-Pharmacological action

Icandelo elisebenzayo le-Saitoteca - misoprostol - yintsimbi eyenziweyo efana ne-prostaglandin yemvelo E1. Kumzimba wesetyhini, i-misoprostol iyayiqonda into eyenziwa yi-uterotonic: yandisa ithoni kwaye isebenze isenzo esivumelwaneni se-muscular smoothness of uterine myometrium. Ngokufanayo, i-cervix iyancipha phantsi kwezenzo zesilwanyana. Ngaloo ndlela, iqanda le-fetal likhishwe, elasekho ngaphantsi kwefuthe leMifepristone lilahlekelwe amandla okuhlala kwisibeleko. Ukupheliswa kokukhulelwa, iSaitotec isetyenziselwa kuphela ngokudibanisa noMifepristone.

Iimpawu eziqhelekileyo zokusebenzisa iipilisi zeSaitotec

I-Mifepristone ne-Saitotec isetyenziswe kwizigaba ezimbini:

• ukuphazamiseka kokukhulelwa okungafunekiyo;
• kwimeko yokukhulelwa okhenkce ;
• xa kwenzeka ukungahambi kakuhle komzimba.

Ukufunyanwa kwezilwanyana zombini zonyango zenziwa kwiziko lezonyango phantsi kolawulo logqirha. Ukukhupha isisu kunye ne-Mifepristone ne-Saitotec kuqhutyelwa kuphela ekukhulelwe kwangaphambili-ukuya kwiintsuku ezingama-49 (iiveki ezi-6 eziphezulu) emva komhla wokuqala wesithanga sokugqibela.

Imiyalelo yokusetyenziswa I-cytoteca inikeza ulwazi olulandelayo malunga neempawu zesicelo kunye nokulinganisa kwesilwanyana:

1. I-dose ephakanyisiweyo yokupheliswa ngokukhuselekileyo kokukhulelwa ngu-400 μg (iipilisi ezimbini ze-Saitoteka), ezithathwa kanye ngomlomo emva kweeyure ezingama-24-36 emva kokuthatha i-Mifepristone.
2. Isiphumo sonyango siqala kuphela imizuzu engama-30 emva kokungeniswa kwaye ihlala kwiiyure ezingama-6; phantse umfazi uqala ukuziva enamandla ukutyumza intlungu kwisisu esezantsi.
3. Uninzi lwezigulana zingaphantsi kweeyure ezingama-6 ziqala ukuphuma kwegazi lomzimba, okubangelwa ukuphuma kwesisu; kwamanye amabhinqa ukuxoshwa kweqanda lomntwana kubonakala ngeveki enye.

Ukuchasana kunye nemiphumo echaphazelekayo yeziyobisi

Ngokwemiyalelo, iSaitotek iyachithwa ukuba isebenzise isisu:

• nabasetyhini abane-hypersensitive to prostaglandins;
• amantombazana angaphantsi kweminyaka eyi-18;
• oongikazi;
• Izigulane ezine-contraceptive zangaphakathi (iisondo, i-spiral, njl);
• kwimeko yokukhulelwa kwe-ectopic okanye ukukhankanywa kwayo;
• phambi kweso sifo sesifo;
• abafazi abanesifo sokuhluthwa, isifo se-asthma, i-glaucoma, izifo ezinzima ze-cardiovascular or endocrine;
• izigulane ezinomsoco okanye ukungazinzi.

Iimbono eziqhelekileyo malunga nokukhuselwa kwezisu zonyango akusoloko ziqinisekiswa ngokwenza. I-Saitotec (ngokusemgangathweni, kunye neMifepristone) ine "izimbali" ezingamnandi, kwaye ngamanye amaxesha iziphumo ezinobungozi zobomi. Ukusetyenziswa kweziyobisi ze-Saitotec ukwenzela ukukhipha isisu kutyalwa:

• ukuphazamiseka kwesifo (isifo sohudo, ukuguqulwa, ukugcoba, ukuhlanza, iintlungu zesisu);
• isikhumba sempembelelo;
• intloko, isisu, iscinezelo segazi esingaqhelekanga;
• ukuxinwa, ukugula;
• utshintshe ubunzima bomzimba;
• ukuphulwa komjikelezo wokuya esikhathini, ubuhlungu, isisindo esinzima;
• ukuhlukana ngokupheleleyo kweqanda lomntwana;
• ukuphuma kwegazi;
• kwikusasa elikufutshane-ukungabikho.