I-ethinylestradiol isebenza njani emzimbeni?
Ngenxa yokuba i-ethinyl estradiol yile iqela le-synthetic steroids, ngoko isenzo salo sifana ne-estradiol yemvelo. Le hormone ixhamla ngokuthe ngqo kwi-esrogen receptors, ezifumaneka kwiiseli zethigethi. Isenzo siza ngokukhawuleza, kuba le nkunkuma ifakwa ngokukhawuleza ngeembrane zomzimba, kunye nesikhumba. Ukudlula kwisibindi, i-ethinyl estradiol i-oxidized, idlula kwelinye ifomu. Le nqubo ihambelana nokubunjwa kweemetabolites ezisesimweni esingasebenzi kwaye zikhutshwe emzimbeni ngomchamo. Ngaloo xesha, izinga lokugqithiswa kwabo lihlukile, kwaye kuxhomekeke kwithuba lokukhulelwa, kunye nesigaba somjikelezo we-ovari kumabhinqa angakhulelweyo.
Kwiimeko ziphi iziyobisi ezichanekileyo eziqukethe i-ethinylestradiol?
Isiphumo esiyinhloko ukuba i-ethinyl estradiol, eqinisweni, ifana ne-estradiol, inomzimba kukugqithisa (ukubuyiswa) kweembrane ezichaphazelekayo. Ngaphantsi kwezenzo zalo, ukuphulukiswa kwe-epithelial kwenzeka, zombini kwiishubhu ze-fallopian kunye nomlomo wesibeleko, kunye nasesisini, izitho zangasese zangaphandle. Ukongezelela, i-ethinyl estradiol ikhuthaza i-motility, ngokuphucula isenzo seziyobisi ezihambelanayo. Kwakhona, le hormone inefuthe le-hypocholesterolemic emzimbeni (ukunciphisa i-cholesterol), ukwandisa izinga le-lipoproteins egazini. Ngenxa yokuba ubukhulu be-insulin buya kwanda, inkqubo yokusetyenziswa kwe-glucose iphucula.
Kwakhona kuyimfuneko ukukhankanya ukuba le nto iyinxalenye yemithi eminingi yokukhulelwa komlomo .
Isidakamizwa esithandwa kakhulu esinezi zinto ziyi-tablet e-Ethinylestradiol. Nangona kunjalo, kukho ezininzi iimpawu ze-ethinyl estradiol. Phakathi kwabo: i-Estrovagin, i- Estrokad , i-Ovestin, iSinestrol kunye nabanye.
Ukuba sithetha ngezidakamizwa, ezibandakanya i-ethinylestadiol, okokuqala, okokuqala, nguYarina, uZhanin, u-Logest, uRigevidon, uMersilon, uLyndynet 30, njl.
Zonke ezi zonyango zichazwe kuphela ngugqirha ngezifo ezahlukahlukeneyo zesifo.