Enye yezona antibiotics ezithandwa kakhulu kwaye zisebenzayo ze-Ceftriaxone, iimiphumo zaso kufuneka zifundwe ngokucophelela njengempawu ngaphambi kokusetyenziswa. Khawucinge ngamanyathelo amanyathelo okumele athatyathwe ngexesha lotyando ngolu hlobo lwe-antimicrobial agent.
Iimpawu Zecala zeCeftriaxone
Ukubanjwa kwesi siza-antibiotic kunokuhamba kunye nokuphendula okuphazamisayo, oko kukuthi: urticaria, ukubetha kunye nokukhawuleza. Kwiimeko ezinqabileyo, kukho i-erythema multiforme, i-bronchospasm okanye i-anaphylactic shock.
Izitho zesisu ziyakwazi ukuphendula ukuthabatha iyeza ngehudo okanye ngokuphambene nokuqhawulwa, kunye nesicefe, ukuphulwa kweengcamango zengcamango. Ngamanye amaxesha umphumo wempembelelo ye-Ceftriaxone ibonakaliswa ngendlela ye-glossitis (ukuvutha kolwimi) okanye i-stomatitis (izilonda ezibuhlungu kwi-mucosa yomlomo). Izigulana zinokukhalaza ngeentlungu zesisu (sinomntu osisigxina).
Ngokukodwa, isibindi siphendula kwi-ceftriaxone: i-transaminases yayo inokunyusa umsebenzi, kunye ne-alkaline phosphatase okanye i-bilirubin. Kwezinye iimeko, kunokwenzeka ukuhlakulela i-pseudocholithiasis ye-gallbladder okanye i-jaundice ye-cholestatic.
Ukuphendula kweengso
Ngokomyalelo, iimpendulo zeCeftriaxone zingaquka ukuphulwa kweentso, ngenxa yokuba izinga legazi liphakama:
- iimveliso ze-nitrogenous metabolic (azotemia);
- i-creatinine (hypercreatininaemia);
- urea.
Umchamo, kwakhona, kunoku:
- i-glucose (glucosuria);
- igazi (hematuria);
- ezibizwa ngokuba yimitshini - iimbumba zeeprotheni okanye izixhobo zamaselula (cylindruria).
Umlinganiselo we-urine ofihliweyo yizintso unganciphisa (oliguria) okanye ufikelele kumanqaku omhlaba (anuria).
Ukuphendula kwe-hematopoietic system
Kwimizimba yokudalwa kwegazi, iilentshi ze Ceftriaxone nazo zinokunika iziphumo ezichaphazelekayo, ezibandakanya ukunciphisa inyunithi yegazi yamacandelo:
- obomvu (i-erythrocytes) - i- anemia ;
- ezimhlophe (i-leukocyte) - i-leukopenia;
- i-leukocyte ye-neutrophilic-neutropenia;
- granulocytes - granulocytopenia;
- i-lymphocytes - lymphocytopenia;
- thrombocytes - thrombocytopenia.
Ukuxinwa kwezinto ze-plasma zokucima kwinqanaba legazi lingahle linciphise, i-hypocoagulation ingenzeka (i-coagulation ephosakeleyo yegazi), echaphazelekayo ngegazi.
Ngelo xesha, kwezinye iimeko, umphumo weCeftriaxone we-leukocytosis, ukwanda kwigazi lamhlophe.
Indawo yasekhaya kunye nezinye iimpendulo
Xa i-antibiotikiti ifakwe kwi-vein, ukuvuvukala kwodonga (iphlebitis) kunokuhlakulela, okanye isigulane siza kuqala ukuva intlungu phakathi kweso sixhobo. Xa izidakamizwa zilawulwa nge-intramuscularly, ngamanye amaxesha ukungena kunye nokuvakalelwa kwintlungu.
Iziphumo ezingezizo ezithile zeCeftriaxone zolawulo zi:
- intloko;
- Candidiasis ;
- ukungcola;
- ukuphuma kumphunga;
- ukungafihlisi (ukuphuhliswa kokuchasene ne-antibiotics, ebangela ukuba isifo esisodwa sibe sikhulu).
Ukugqithisa nokusetyenziswa kweziyobisi
Kwimeko yokugqithisa ngokweqile, unyango lwezonyango luyenziwa. Ayikho i-antidote ethile ekupheliseni umphumo weCeftriaxone; i-hemodialysis ayikwazi. Ngoko ke,
I-Ceftriaxone inezinye izinto ezingalunganga: iphazamisa umkhiqizo we-vitamin K, ngenxa yokuba, njengawo nawuphi na ulwaphulo-mthetho, lugqithisa i-intestinal flora, ngoko-ke akufanele kuthathe izidakamizwa ezichasene ne-steroidal-oku kungandisa ingozi yokuphuma kwamanzi. Iyeza lingahambelani ne-ethanol, ngoko ukutywala kotywala ngexesha lonyango lichazwe.
Aminoglycosides kunye neCeftriaxone, esebenza ngokubambisana, ukuphucula umphumo womnye nomnye (i-synergy) ngokuchasene ne-gram-negative microbes.