Antifospholipid syndrome kunye nokukhulelwa

I-Antiphospholipid syndrome (APS) liqela leengxaki ezizimelayo ezibonakaliswa ngokubunjwa kwenani elikhulu lama-antibodies kuma-phospholipids ekhoyo kwi-plasma yegazi (i-antiphospholipid antibodies). Phakathi kwabasetyhini abanesifo sokuphuphuma komzimba , iziganeko ze-antiphospholipid syndrome ziphezulu kwaye zi-28-43%. Inkxalabo eyintloko yolu luhlu luyi-thrombosis.

Ziziphi izizathu eziphambili zophuhliso lwe-APS?

Izizathu zokuphuhliswa kwe-antiphospholipid syndrome zimbalwa. Ezi zifo ziyakhula kwiimeko ezilandelayo:

1. Xa ibhinqa igula nge- systemic lupus erythematosus .
2. Ubukho kwi-anamnesis ye-thrombosis. Xa iinqanawa eziphazamisayo zinika igazi emathumbu, oko kuthiwa "umlenze wesisu" kukhula, ebonakala ngokubonakala koxinzelelo, ukunyamezela intlungu kwisisu esiswini emva kokungena.
3. Ukunciphisa iiplatelet egazini, ezingenakudityaniswa neziganeko zentsholongwane.
4. Ubukho bembali ye-myocardial infarction kunye nezinye izifo ezinxulumene neengxaki zentsholongwane yomzimba.

I-antiphospholipid syndrome ibonakala njani?

Iimpawu ze-antiphospholipid syndrome, kuxhomekeke ngqo kwiimeko ezininzi. Ngoko kubaluleke kakhulu ezi zinto zilandelayo:

• ubungakanani kunye nendawo yeempahla ezichaphazelekayo ngokugula;
• inkqubo yokuvala i-lumen kubo.

Ngoko, kwimeko xa kukho ukukhutshwa kweenqanawa ezincinci, ukuphulwa ngokukhawuleza kwemisebenzi yelungu elizidlayo ligcinwa. Ngokomzekelo, ukuba ukukhangela kwamathambo amancinci amancinci kukuphazamiseka, kukho ukuphulwa kwemvumelwano yecandelo ngalinye le-myocardium, kodwa ukuba i-lumen ye-coronary artery ivaliwe, i-infyoction ye-myocardial iya kwenzeka.

Ngokuqhelekileyo i-antiphospholipid syndrome kubasetyhini abakhulelweyo banokulinganisa ezinye iintlobo zempilo, ezibonakaliswa yimpawu ezifanayo. Ngaloo ndlela, iimpawu ze-antiphospholipid syndrome ziyakubonakaliswa phambi kobuchopho obunobuncwane (i-lacy, isitya esincinci seenqanawa ekhanda). Kwakhona, izilonda ezingapheliyo zine-shin, ezinzima ukunyanga, kunye ne-paripheral gangrene, zingabonisa ukuba kukho ukukhubazeka emzimbeni.

Unokwenziwa njani unyango?

Unyango lwe-antiphospholipid syndrome ekukhulelweni kuqhutywa phantsi kolawulo loogqirha ababini: i-gynecologist kunye ne-rheumatologist. Ulwaphulo oluphambili lwale ntsholongwane kukusetyenziswa kwe-glucocorticoids kunye ne-cytostatics. Ngomxholo ophezulu we-antibodies egazini, isisombululo kuphela ukuqhuba i-plasmapheresis (ukuhlanjululwa kwegazi).